Evidence map›Paper›PMID 35500879›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

The Impact of Social Distancing in 2020 on Admission Rates for Exacerbations in Asthma: A Nationwide Cohort Study.

Louise Lindhardt Toennesen, Barbara Bonnesen, Pradeesh Sivapalan, Alexander Svorre Jordan, Mohamad Isam Saeed, Josefin Eklöf, Charlotte Suppli Ulrik, Kristoffer Grundtvig Skaarup, Mats Christian Højberg Lassen, Tor Biering-Sørensen and 1 more

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Louise Lindhardt ToennesenSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark; Department of Respiratory Medicine, Copenhagen University Hospital, Hvidovre, Denmark. Electronic address: louise.toennesen@gmail.com.
Barbara BonnesenSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Pradeesh SivapalanSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark; Department of Internal Medicine, Zealand Hospital, University of Copenhagen, Roskilde, Denmark.
Alexander Svorre JordanSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Mohamad Isam SaeedSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Josefin EklöfSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Charlotte Suppli UlrikDepartment of Respiratory Medicine, Copenhagen University Hospital, Hvidovre, Denmark.
Kristoffer Grundtvig SkaarupDepartment of Cardiology, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Mats Christian Højberg LassenDepartment of Cardiology, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Tor Biering-SørensenDepartment of Cardiology, Copenhagen University Hospital, Herlev-Gentofte, Denmark.
Jens-Ulrik Stæhr JensenSection of Respiratory Medicine, Copenhagen University Hospital, Herlev-Gentofte, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen.
Gentofte Hospital · DKCopenhagen University Hospital · DKUniversity of Copenhagen · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial distancing measures introduced during the coronavirus disease 2019 pandemic have reduced admission rates for various infectious and noninfectious respiratory diseases. We hypothesized that rates of asthma exacerbations would decline following the national lockdown in Denmark.

objectiveTo determine weekly rates of in- and out-of-hospital asthma exacerbations before and during the social distancing intervention implemented on March 12, 2020.

methodsAll individuals older than 18 years with at least 1 outpatient hospital contact with asthma as the main diagnosis from January 1, 2013, to December 31, 2017, were included. Weekly asthma exacerbation rates from January 1, 2018, to May 22, 2020, were calculated. An interrupted time-series model with the lockdown on March 12, 2020, as the point of interruption was used.

resultsA total of 38,225 patients with asthma were identified. The interrupted time-series model showed no immediate fall in exacerbation rates during the first week after March 12, 2020. However, there was a significant decline in weekly exacerbation rates in the following 10 weeks (change in trend for exacerbations requiring hospitalization: -0.75 [95% CI, -1.39 to -0.12]; P < .02 and in all asthma exacerbations: -12.2 [95% CI, -19.1 to -5.4; P < .001), amounting to a reduction of approximately 1 and 16.5 exacerbations per year per 100 patients in the cohort, respectively.

conclusionsThe introduction of the social distancing measures in Denmark did not lead to an immediate reduction in asthma exacerbation rates; however, a gradual decline in exacerbation rates during the following 10-week period was observed.

Indexed as

AsthmaCOVID-19Cohort StudiesCommunicable Disease ControlDisease ProgressionHospitalizationHumansPhysical DistancingAsthmaEpidemiologyExacerbationsLockdownSocial distancing

Identifiers

PMID35500879
PMCPMC9352355
OpenAlexW4225164121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.