Evidence map›Paper›PMID 35500710›Full record

ArticleThe Science of the total environment2022

In silico evidence of antiviral activity against SARS-CoV-2 main protease of oligosaccharides from Porphyridium sp.

Hajer Ben Hlima, Ameny Farhat, Sarra Akermi, Bassem Khemakhem, Youssef Ben Halima, Philippe Michaud, Imen Fendri, Slim Abdelkafi

Open access · greenAbstract read
In one paragraph

Article in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Glucans, Paramylon and Other Algae Bioactive Molecules.International journal of molecular sciences · 2023
    Article
  6. Review
  7. Marine AlgaMarine drugs · 2022
    Article
  8. Paramylon and Other Bioactive Molecules in Micro and Macroalgae.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hajer Ben HlimaLaboratoire de Génie Enzymatique et Microbiologie, Equipe de Biotechnologie des Algues, Ecole Nationale d'Ingénieurs de Sfax, University of Sfax, Sfax, Tunisia.
Ameny FarhatLaboratoire de Biotechnologies des Plantes Appliquées à l'Amélioration des Cultures, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Sarra AkermiLaboratory of Microorganisms and Biomolecules of the Centre of Biotechnology of Sfax, Tunisia.
Bassem KhemakhemLaboratoire de Biotechnologies des Plantes Appliquées à l'Amélioration des Cultures, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Youssef Ben HalimaRIADI Labs, National School of Computer Science, Manouba University, Manouba, Tunisia.
Philippe MichaudInstitut Pascal, Université Clermont Auvergne, CNRS, Clermont Auvergne INP, F-63000 Clermont-Ferrand, France.
Imen FendriLaboratoire de Biotechnologies des Plantes Appliquées à l'Amélioration des Cultures, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Slim AbdelkafiLaboratoire de Génie Enzymatique et Microbiologie, Equipe de Biotechnologie des Algues, Ecole Nationale d'Ingénieurs de Sfax, University of Sfax, Sfax, Tunisia. Electronic address: slim.abdelkafi@enis.tn.
University of Sfax · TNCentre of Biotechnology of Sfax · TNInstitut Pascal · FRManouba University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus pandemic (COVID-19) has created an urgent need to develop effective strategies for prevention and treatment. In this context, therapies against protease M

Indexed as

COVID-19PorphyridiumAntiviral AgentsCoronavirus 3C ProteasesHumansMolecular Docking SimulationMolecular Dynamics SimulationOligosaccharidesProtease InhibitorsSARS-CoV-23C-like proteinase, SARS-CoV-2Antiviral AgentsCoronavirus 3C ProteasesOligosaccharidesProtease InhibitorsDockingInhibitorsMicroalgaePolysaccharidePorphyridiumSARS-CoV-2

Identifiers

PMID35500710
PMCPMC9052773
OpenAlexW4225131807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.