Evidence map›Paper›PMID 35500315›Full record

ArticleClinical nutrition (Edinburgh, Scotland)2022

Differential hydrogen sulfide production by a human cohort in response to animal- and plant-based diet interventions.

Levi Teigen, Prince P Mathai, Sharon Lopez, Michael Matson, Baila Elkin, Daria Kozysa, Amanda J Kabage, Matthew Hamilton, Byron P Vaughn, Michael J Sadowsky and 1 more

Open access · greenAbstract read
In one paragraph

Article in Clinical nutrition (Edinburgh, Scotland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Significance of GSH and HRedox report : communications in free radical research · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Levi TeigenDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Prince P MathaiBioTechnology Institute, University of Minnesota, St. Paul, MN, USA.
Sharon LopezDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Michael MatsonDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Baila ElkinMedical School, University of Minnesota, Minneapolis, MN, USA.
Daria KozysaDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Amanda J KabageDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Matthew HamiltonBioTechnology Institute, University of Minnesota, St. Paul, MN, USA.
Byron P VaughnDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
Michael J SadowskyBioTechnology Institute, University of Minnesota, St. Paul, MN, USA; Department of Soil, Water, and Climate, USA; Department of Plant and Microbial Biology, USA.
Alexander KhorutsDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Minnesota, Minneapolis, MN, USA; BioTechnology Institute, University of Minnesota, St. Paul, MN, USA; Center for Immunology, University of Minnesota, Minneapolis, MN, USA. Electronic address: khoru001@umn.edu.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

Medical Student Summer Research Program in Infection and ImmunityT35AI118620 · NIAID · UNIVERSITY OF MINNESOTA · PI MUELLER, DANIEL L · 2015 to 2025
$351k
NIAID NIH HHS T35 AI118620
6 · The paper itself

Abstract

backgroundHydrogen sulfide (H

objectiveDetermine the effect of short-term (1-week) plant- and animal-based eating patterns on ex vivo fecal H

methodsThe study design was an open-label, cross-over diet study and diets were self-administered. Each participant consumed two interventional diets: 1) an animal-based, low fiber (i.e. western) diet and 2) a plant-based, high fiber diet, separated by a two-week washout period. Participants collected full stool samples at the end of each week, which were processed within 2 h of collection to capture H

resultsMedian H

conclusionsHere we report that substrate changes associated with a 1-week plant-based diet intervention resulted in lower ex vivo H

Indexed as

Hydrogen SulfideAnimalsCross-Over StudiesDietDietary FiberDiet, VegetarianHumansHydrogenDietary FiberHydrogenHydrogen Sulfide16S rRNA geneDietary sulfurHydrogen sulfideMicrofluidic qPCRSulfate-reducing bacteria

Identifiers

PMID35500315
PMCPMC11082741
OpenAlexW4223939224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.