Evidence map›Paper›PMID 35500249›Full record

Trial reportTrends in psychiatry and psychotherapy2023

Randomized trial of the efficacy of trial-based cognitive therapy for obsessive-compulsive disorder: preliminary findings.

Eleonardo Pereira Rodrigues, Ana Jardel Batista Fechine, Antonio César Oliveira, Cristiane Francisca Ferreira Matos, Cristiane de Medeiros Passarela, Curt Hemanny, Francimeuda de Morais Dias, José Wilson Batista, Luciana de Carvalho Nogueira Albuquerque, Myrla Sirqueira Soares and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Trends in psychiatry and psychotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Eleonardo Pereira RodriguesPrograma de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, BA, Brazil. Laboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Ana Jardel Batista FechineLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Antonio César OliveiraLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Cristiane Francisca Ferreira MatosLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Cristiane de Medeiros PassarelaNYC Cognitive Therapy, New York, NY, USA.
Curt HemannyPrograma de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas, Universidade Federal da Bahia, Salvador, BA, Brazil.
Francimeuda de Morais DiasLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
José Wilson BatistaLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Luciana de Carvalho Nogueira AlbuquerqueLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Myrla Sirqueira SoaresLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Pedro Evangelista CoelhoLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Vanessa Pires de Carvalho AraújoLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Zila Mendes AyresLaboratório de Neurociência Cognitiva, Curso de Psicologia, Universidade Estadual do Piauí, Teresina, PI, Brazil.
Irismar Reis de OliveiraPrograma de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, BA, Brazil. Programa de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas, Universidade Federal da Bahia, Salvador, BA, Brazil.

Funding

Pró-Reitoria de Pesquisa
6 · The paper itself

Abstract

introductionObsessive-compulsive disorder (OCD) is the fourth most prevalent mental disorder and is a disabling condition. OCD is associated with anatomical and functional changes in the brain, in addition to dysfunctional cognitions. The treatments of choice are selective serotonin reuptake inhibitors, cognitive-behavioral therapy (CBT), and exposure and response prevention (ERP). Trial-based cognitive therapy (TBCT) is a recent and empirically validated psychotherapy with a focus on restructuring dysfunctional negative core beliefs (CBs). The objective of this study was to evaluate the efficacy of TBCT relative to ERP for treatment of OCD.

methodA randomized, single-blind clinical trial was conducted, randomizing 26 patients for individual treatment with TBCT (n = 12) or ERP (n = 14). The groups were evaluated at baseline, at the end of 3 months (12 sessions), and at 3, 6, and 12-month follow-ups.

resultsBoth approaches reduced the severity of symptoms with large effect sizes. These results were maintained at the 12-month follow-up assessment.

conclusionTBCT may be a valid and promising treatment for this disorder.

Indexed as

Cognitive Behavioral TherapyObsessive-Compulsive DisorderCombined Modality TherapyHumansSelective Serotonin Reuptake InhibitorsSingle-Blind MethodTreatment OutcomeSelective Serotonin Reuptake Inhibitorscognitive-behavioral therapyexposure and response preventionObsessive-compulsive disorderrandomized clinical trialtrial-based cognitive therapy

Identifiers

PMID35500249
PMCPMC10597383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.