Evidence map›Paper›PMID 35499804›Full record

ReviewOphthalmology and therapy2022

The State of Patient-Reported Outcome Measures for Pediatric Patients with Inherited Retinal Disease.

Kavin Selvan, Maria F Abalem, Gabrielle D Lacy, Ajoy Vincent, Elise Héon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Ophthalmology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kavin SelvanGenetics and Genome Biology (GGB) Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-2051-9577
Maria F AbalemDepartment of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, MI, USA.
Gabrielle D LacyDepartment of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, MI, USA.
Ajoy VincentGenetics and Genome Biology (GGB) Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada.
Elise HéonGenetics and Genome Biology (GGB) Program, The Hospital for Sick Children Research Institute, Toronto, ON, Canada. elise.heon@sickkids.ca.ORCID http://orcid.org/0000-0003-4143-9311

Funding

Foundation Fighting Blindness CD-CL-0617-0727-HSCHospital for Sick Children The Henry Brent Chair in Innovative Pediatric Ophthalmology ResearchUniversity of Toronto and University Health Network Vision Science Research Program
6 · The paper itself

Abstract

Patient-reported outcome measures (PROMs) are questionnaires that assess health outcomes meaningful to the patient. PROMs have multiple applications, such as supporting clinicians' decision-making for patient care, understanding the impact of disease on patient functioning, and evaluating the efficacy of therapeutics. Though PROMs were developed for various eye conditions, no PROM was tailored to pediatric patients with inherited retinal disease (IRD). Hence, a literature search was conducted using MEDLINE and Embase to identify PROMs potentially relevant to this patient population. This review evaluated selected pediatric PROMs against the US Food and Drug Administration (FDA) guidelines and found restricted use in the context of IRD. As there is a need for PROMs tailored to pediatric patients with IRD, we provide a perspective on applying the International Society for Pharmacoeconomics and Outcomes Research and FDA standards on the development of PROMs specific to IRD.

Indexed as

Clinical trialGenetic therapyOphthalmologyPatient-reported outcomePediatricsRetinal diseasesVision impairment

Identifiers

PMID35499804
PMCPMC9114271

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.