Evidence map›Paper›PMID 35499500›Full record

ArticleVascular and endovascular surgery2022

Combined Treatment With Carotid Endoarterectomy and Coronary Artery Bypass Grafting: A Single-Institutional Experience in 222 Patients.

Pietro Modugno, Veronica Picone, Enrico Maria Centritto, Eugenio Calvo, Carlo Canosa, Felice Piancone, Nicola Testa, Nicola Camposarcone, Gaetano Castellano, Pasquale Astore and 4 more

Open access · greenAbstract read
In one paragraph

Article in Vascular and endovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Pietro ModugnoVascular Surgery Unit, 18654Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.ORCID https://orcid.org/0000-0002-8194-7567
Veronica PiconeVascular Surgery Unit, 18654Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Enrico Maria CentrittoVascular Surgery Unit, 18654Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Eugenio CalvoCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Carlo CanosaCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Felice PianconeCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Nicola TestaCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Nicola CamposarconeIntensive Care Unit, Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Gaetano CastellanoIntensive Care Unit, Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Pasquale AstoreIntensive Care Unit, Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Luigi Di MartinoIntensive Care Unit, Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Fabrizio Di IustoCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Carlo Maria De FilippoCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Massimo MassettiCardiac Surgery Unit, 96986Gemelli Molise Hospital, Catholic University of Sacred Heart, Campobasso, Italy.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCarotid atherosclerotic disease is a known independent risk factor of post operative stroke after coronary artery bypass grafting (CABG). The best management of concomitant coronary artery disease and carotid artery disease remains debated. Current strategies include simultaneous carotid endoarterectomy (CEA) and CABG, staged CEA followed by CABG, staged CABG followed by CEA, staged transfemoral carotid artery stenting (TF-CAS) followed by CABG, simultaneous TF-CAS and CABG and transcarotid artery stenting.

methodsWe report our experience based on a cohort of 222 patients undergoing combined CEA and CABG surgery who come to our observation from 2004 to 2020. All patients with >70% carotid stenosis and severe multivessel or common truncal coronary artery disease underwent combined CEA and CABG surgery at our instituion. 30% of patients had previously remote neurological symptoms or a cerebral CT-scan with ischemic lesions. Patients with carotid stenosis >70%, either asymptomatic or symptomatic, underwent CT-scan without contrast media to assess ischemic brain injury, and in some cases, if necessary, CT-angiography of the neck and intracranial vessels.

resultsThe overall perioperative mortality rate was 4.1% (9/222 patients). Two patients (.9%) had periprocedural ipsilateral transient ischemic attack (TIA) which completely resolved by the second postoperative day. Two patients (.9%) had an ipsilateral stroke, while 7 patients (3.2%) had a stroke of the controlateral brain hemisphere. Two patients (.9%) patients were affected by periprocedural coma caused by cerebral hypoperfusion due to perioperative heart failure. There were no statistically significant differences between patients in Extracorporeal Circulation (ECC) and Off-pump patients in the onset of perioperative stroke.

conclusionOur experience reported that combined surgical treatment of CEA and CABG, possibly Off-Pump, is a feasible treatment procedure, able to minimize the risk of post-operative stroke and cognitive deficits.

Indexed as

Carotid Artery DiseasesCarotid StenosisCoronary Artery DiseaseEndarterectomy, CarotidStrokeCoronary Artery BypassHumansStentsTreatment Outcomecarotidcoronarycoronary artery bypass grafting

Identifiers

PMID35499500
PMCPMC10233500
OpenAlexW4225277332

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.