Evidence map›Paper›PMID 35499323›Full record

ArticleJournal of virology2022

Heterogeneity of Latency Establishment in the Different Human CD4

Giacomo M Butta, Giorgio Bozzi, Greta Gallo, Gaia Copaloni, Chiara Cordiglieri, Mariacristina Crosti, Marilena Mancino, Daniele Prati, Viviana Simon, Andrea Gori and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Giacomo M ButtaINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Giorgio BozziFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Diseases Unit, Department of Internal Medicine, Milan, Italy.
Greta GalloINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Gaia CopaloniINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Chiara CordiglieriINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Mariacristina CrostiINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Marilena MancinoINGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Daniele PratiDepartment of Transfusion Medicine and Hematology, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Viviana SimonDepartment of Microbiology, Icahn School of Medicine at Mount Sinaigrid.59734.3c, New York, New York, USA.
Andrea GoriFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Diseases Unit, Department of Internal Medicine, Milan, Italy.
Alessandra BanderaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Infectious Diseases Unit, Department of Internal Medicine, Milan, Italy.ORCID 0000-0001-9440-4601
Raffaele De Francesco *INGM-Istituto Nazionale di Genetica Molecolare, Virology, Milan, Italy.
Lara Manganaro *Università degli Studi di Milano, Department of Pharmacological and Biomolecular Sciences, Milan, Italy.ORCID 0000-0003-2743-2658
Istituto Nazionale Genetica Molecolare · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV integrates into the host genome, creating a viral reservoir of latently infected cells that persists despite effective antiretroviral treatment. CD4-positive (CD4

Indexed as

CD4-Positive T-LymphocytesHIV InfectionsInterleukin-15Virus LatencyHIV-1HumansNF-kappa BProvirusesT-Lymphocyte SubsetsInterleukin-15NF-kappa BCD4 T subsetsHIVIL-15latency

Identifiers

PMID35499323
PMCPMC9131862
OpenAlexW4225277453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.