Evidence map›Paper›PMID 35499322›Full record

ArticleJournal of virology2022

TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.

Sujie Dong, Ning Kong, Yu Zhang, Youwen Li, Dage Sun, Wenzhen Qin, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye and 9 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Sujie Dong *Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Ning Kong *Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Yu Zhang *Department of Preventive Dentistry, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Youwen Li *College of Animal Science, Tarim University, Xinjiang, China.
Dage SunShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Wenzhen QinShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Huanjie ZhaiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Xueying ZhaiShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Xinyu YangShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Chenqian YeShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Manqing YeShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Changlong LiuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Lingxue YuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Hao ZhengShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Wu TongShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Hai YuShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Wen ZhangSchool of Medicine, Jiangsu University, Zhenjiang, China.
Guangzhi TongShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Tongling ShanShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.ORCID 0000-0002-5329-6349
Shanghai Veterinary Research Institute · CNTarim University · CNJiangsu University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In global infection and serious morbidity and mortality, porcine epidemic diarrhea virus (PEDV) has been regarded as a dreadful porcine pathogen, but the existing commercial vaccines are not enough to fully protect against the epidemic strains. Therefore, it is of great necessity to feature the PEDV-host interaction and develop efficient countermeasures against viral infection. As an RNA/DNA protein, the

Indexed as

Coronavirus InfectionsDNA-Binding ProteinsInterferon Type IPorcine epidemic diarrhea virusVirus ReplicationAnimalsImmunity, InnateInterferon Regulatory Factor-3Myeloid Differentiation Factor 88Nucleocapsid ProteinsRNASignal TransductionSwineTNF Receptor-Associated Factor 3DNA-Binding ProteinsInterferon Regulatory Factor-3Interferon Type IMyeloid Differentiation Factor 88Nucleocapsid ProteinsRNATNF Receptor-Associated Factor 3IFN-Inucleocapsid proteinPEDVselective autophagyTARDBP

Identifiers

PMID35499322
PMCPMC9131865
OpenAlexW4225291039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.