Evidence map›Paper›PMID 35499278›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Sex differences in Epworth Sleepiness Scale normalization with continuous positive airway pressure.

Matthew T Scharf, Peng Zhang, Nathan A Walker, Mariam Mirza, Aesha M Jobanputra, R Nisha Aurora, Jag Sunderram, Shou-En Lu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Matthew T ScharfDepartment of Neurology, Rutgers/Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Peng ZhangSchool of Public Health, Rutgers University, Piscataway, New Jersey.
Nathan A WalkerSleep Center, Department of Neurology, University of North Carolina, Chapel Hill, North Carolina.
Mariam MirzaSchool of Arts and Science, Rutgers University, New Brunswick, New Jersey.
Aesha M JobanputraSleep Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rutgers/Robert Wood Johnson Medical School, New Brunswick, New Jersey.
R Nisha AuroraSleep Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rutgers/Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Jag SunderramSleep Center, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rutgers/Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Shou-En LuSchool of Public Health, Rutgers University, Piscataway, New Jersey.
Johnson University · USRutgers, The State University of New Jersey · USEnvironmental and Occupational Health Sciences Institute · USUniversity of North Carolina at Chapel Hill · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

STUDY

objectivesContinuous positive airway pressure (CPAP) improves sleepiness in patients with obstructive sleep apnea, but some patients remain sleepy. The objective of this study was to identify determinants that are associated with improvements in self-reported sleepiness in patients with obstructive sleep apnea on CPAP therapy.

methodsA retrospective cohort study was performed in a clinic-based population to determine which variables contributed to the improvement in the Epworth Sleepiness Scale (ESS) in patients on CPAP therapy for OSA, stratified by baseline ESS score (< 11 or ≥ 11). Variables associated with ESS scores normalizing with CPAP were also assessed.

resultsPatients with a baseline high ESS score showed greater improvements in the ESS with CPAP. When looking at interactions between baseline ESS classification and changes in ESS, we found that a higher apnea-hypopnea index was only associated with improvement in the ESS among patients with a high baseline ESS. Other assessed factors or covariates were not significantly different. When looking at ESS normalization, we found that female sex and lower body mass index were associated with a lower likelihood of ESS normalization. The difference in the rate of ESS normalization between females and males was higher with more days on CPAP.

conclusionsOf all the assessed factors and covariates, only the apnea-hypopnea index was associated with the change in the ESS differently in patients with a high or normal baseline ESS score. ESS normalization rates were lower in females than in males, and this disparity was amplified by more days on CPAP. CITATION: Scharf MT, Zhang P, Walker NA, et al. Sex differences in Epworth Sleepiness Scale normalization with continuous positive airway pressure.

Indexed as

Continuous Positive Airway PressureSleep Apnea, ObstructiveFemaleHumansMaleRetrospective StudiesSex CharacteristicsSleepinessTreatment OutcomeCPAPEpworth Sleepiness ScaleOSAsex

Identifiers

PMID35499278
PMCPMC9435344
OpenAlexW4225263306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.