Evidence map›Paper›PMID 35499159›Full record

ArticleACS nano2022

Electrical Stimulation of Neurons with Quantum Dots via Near-Infrared Light.

Onuralp Karatum, Humeyra Nur Kaleli, Guncem Ozgun Eren, Afsun Sahin, Sedat Nizamoglu

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Light-Harvesting Photothermal Hotspots Enabled by NIR Scattering-Absorption Coupling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Stimuli-Responsive Materials for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Perspectives on Multiscale Colloid-Based Materials for Biomedical Applications.Langmuir : the ACS journal of surfaces and colloids · 2023
    Review
  18. Review
  19. MnOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Onuralp KaratumDepartment of Electrical and Electronics Engineering, Koc University, Istanbul 34450, Turkey.ORCID 0000-0002-7669-9589
Humeyra Nur KaleliResearch Center for Translational Medicine, Koc University, Istanbul 34450, Turkey.ORCID 0000-0002-4355-7592
Guncem Ozgun ErenDepartment of Biomedical Science and Engineering, Koc University, Istanbul 34450, Turkey.ORCID 0000-0002-9297-9898
Afsun SahinResearch Center for Translational Medicine, Koc University, Istanbul 34450, Turkey.ORCID 0000-0002-5083-5618
Sedat NizamogluDepartment of Electrical and Electronics Engineering, Koc University, Istanbul 34450, Turkey.ORCID 0000-0003-0394-5790
Koç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photovoltaic biointerfaces offer wireless and battery-free bioelectronic medicine via photomodulation of neurons. Near-infrared (NIR) light enables communication with neurons inside the deep tissue and application of high photon flux within the ocular safety limit of light exposure. For that, nonsilicon biointerfaces are highly demanded for thin and flexible operation. Here, we devised a flexible quantum dot (QD)-based photovoltaic biointerface that stimulates cells within the spectral tissue transparency window by using NIR light (λ = 780 nm). Integration of an ultrathin QD layer of 25 nm into a multilayered photovoltaic architecture enables transduction of NIR light to safe capacitive ionic currents that leads to reproducible action potentials on primary hippocampal neurons with high success rates. The biointerfaces exhibit low in vitro toxicity and robust photoelectrical performance under different stability tests. Our findings show that colloidal quantum dots can be used in wireless bioelectronic medicine for brain, heart, and retina.

Indexed as

Quantum DotsElectric StimulationInfrared RaysNeuronsPhotonselectrical stimulationnear-infraredneural stimulationoptical stimulationphotovoltaicquantum dot

Identifiers

PMID35499159
PMCPMC9134491
OpenAlexW4225290430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.