Evidence map›Paper›PMID 35499050›Full record

ArticleJournal of advanced research2022

Genetic divergence and functional convergence of gut bacteria between the Eastern honey bee

Yuqi Wu, Yufei Zheng, Shuai Wang, Yanping Chen, Junyi Tao, Yanan Chen, Gongwen Chen, Hongxia Zhao, Kai Wang, Kun Dong and 3 more

Abstract read
In one paragraph

Article in Journal of advanced research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. DietaryInsects · 2026
    Article
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  5. Review
  6. Article
  7. Article
  8. Review
  9. Gut microbiota of BrazilianbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Host Specificity ofInsects · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yuqi WuCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Yufei ZhengCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Shuai WangCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Yanping ChenUSDA-ARS Bee Research Laboratory, Beltsville, MD, USA.
Junyi TaoDepartment of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
Yanan ChenCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Gongwen ChenCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Hongxia ZhaoGuangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou, China.
Kai WangInstitute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.
Kun DongEastern Bee Research Institute, College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan, China.
Fuliang HuCollege of Animal Sciences, Zhejiang University, Hangzhou, China.
Ye FengSir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huoqing ZhengCollege of Animal Sciences, Zhejiang University, Hangzhou, China.

Funding

NIEHS NIH HHS 27304C2054
6 · The paper itself

Abstract

Introduction: The functional relevance of intra-species diversity in natural microbial communities remains largely unexplored. The guts of two closely related honey bee species, Objectives: We aim to assess the functional relevance of intra-species diversity of Methods: Honey bee workers were collected from four regions of China. Their gut microbiomes were investigated by shotgun metagenomic sequencing, and the bacterial compositions were compared at the species level. A cross-species colonisation assay was conducted, with the gut metabolomes being characterised by LC-MS/MS. Results: Comparative analysis showed that the strain composition of the core bacterial species was host-specific. These core bacterial species presented distinctive functional profiles between the hosts. However, the overall functional profiles of the Conclusion: Our findings revealed functional differences in most core gut bacteria between the guts of

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaBeesChromatography, LiquidMetagenomeTandem Mass SpectrometryABC, ATP-binding cassetteAc, Apis ceranaAcBJ, A. cerana workers sampled in BeijingAcc, A. cerana workers with A. cerana gut microbiotaAcGZ, A. cerana workers sampled in GuangzhouAcHZ, A. cerana workers sampled in HangzhouAcKM, A. cerana workers sampled in KunmingAcm, A. cerana workers with A. mellifera gut microbiotaAm, Apis melliferaAmBJ, A. mellifera workers sampled in BeijingAmc, A. mellifera workers with A. cerana gut microbiotaAmGZ, A. mellifera workers sampled in GuangzhouAmHZ, A. mellifera workers sampled in HangzhouAmKM, A. mellifera workers sampled in KunmingAmm, A. mellifera workers with A. mellifera gut microbiotaApis ceranaApis melliferaCAZyme, Carbohydrate-active enzymeCTAB, Cetyltrimethyl Ammonium BromideFDR, False Discovery RateGO, Gene ontologyGut microbiotaHMDB, Human metabolites databaseIntra-species diversityKEGG, Kyoto Encyclopedia of Genes and GenomesKO, KEGG orthologLCA, Lowest common ancestor-based algorithmLC-MS, Liquid chromatography mass spectrometryMetabolomeMetagenomeNCBI, National Center of Biotechnology Information, USAORFs, Open reading framesPBS, Phosphate Buffer SalinePCA, Principal component analysisPCoA, Principal coordinates analysisPTS, Phosphotransferase systemSNP, Single nucleotide polymorphismSNVs, Single nucleotide variantsSRA, Sequence read archiveVIP, Variable important in projection

Identifiers

PMID35499050
PMCPMC9039653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.