Evidence map›Paper›PMID 35499048›Full record

ArticleJournal of advanced research2022

CRISPR/Cas9 mediated disruption of

Saira Ibrahim, Bilal Saleem, Nazia Rehman, Syed Adeel Zafar, Muhammad Kashif Naeem, Muhammad Ramzan Khan

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 134 citations in OpenAlex.

  1. Review
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  5. Advances in CRISPR Plant Applications.International journal of molecular sciences · 2026
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  7. Biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Saira IbrahimGenome Editing and Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University Islamabad, Pakistan.
Bilal SaleemGenome Editing and Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University Islamabad, Pakistan.
Nazia RehmanNational Institute for Genomic and Advanced Biotechnology, National Agricultural Research Centre, Park Road, Islamabad Pakistan.
Syed Adeel ZafarNational Institute for Genomic and Advanced Biotechnology, National Agricultural Research Centre, Park Road, Islamabad Pakistan.
Muhammad Kashif NaeemNational Institute for Genomic and Advanced Biotechnology, National Agricultural Research Centre, Park Road, Islamabad Pakistan.
Muhammad Ramzan KhanGenome Editing and Sequencing Lab, National Centre for Bioinformatics, Quaid-i-Azam University Islamabad, Pakistan.
Quaid-i-Azam University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Phytic acid (PA) is an important antinutrient agent present in cereal grains which reduces the bioavailability of iron and zinc in human body, causing malnutrition. Objective: A recent genome editing tool CRISPR/Cas9 has been successfully applied to develop biofortified rice by disrupting Methods: In this study, we isolated 3 Results: We got several genome-edited lines in the T Conclusion: Our study demonstrates the potential application of CRISPR/Cas9 technique for the rapid generation of biofortified wheat cultivars.

Indexed as

Phytic AcidTriticumCRISPR-Cas SystemsEdible GrainHumansInositol PhosphatesIronZincinositol pentaphosphateInositol PhosphatesIronPhytic AcidZincBiofortificationCRISPR/Cas9IronPhytic acidZinc

Identifiers

PMID35499048
PMCPMC9039650
OpenAlexW3182262425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.