ArticleFood chemistry: X2022
Dual-color blending based visual LAMP for food allergen detection: A strategy with enlarged color variation range and contrast.
Article in Food chemistry: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Sensitive and rapid detection ofFrontiers in cellular and infection microbiology · 2026Article
- Triple-mode point-of-care diagnostics for high-risk human papillomavirus in urine.Biosensors & bioelectronics: X · 2025Article
- Review
- Parvalbumin Gene: A Valuable Marker for Pike Authentication and Allergen Risk Assessment.Journal of agricultural and food chemistry · 2024Article
- A microfluidic diagnostic device with air plug-in valves for the simultaneous genetic detection of various food allergens.Scientific reports · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Food allergy has been a serious public health problem around the world. Its prevention relies heavily on the effective avoidance of any contaminated food, making clear and accurate detection very important. LAMP is one of the most potent methods for allergen rapid detection. However, its current colorimetric readouts usually have low color contrast and narrow color variation range. Thus, here we proposed a strategy based on color evolution to enlarge the variation range as well as the contrast to improve its suitability for naked-eye observation. By simply blending two commonly used color change processes during amplification, a wider color variation window, and a near contrast color change, purple-to-green with a hues difference of 10 were obtained. Three important allergens (walnuts, hazelnuts, and peanuts) were tested with a comparable sensitivity towards fluorescent real-time LAMP. Its feasibility for practical use has also been studied. This simple but effective strategy provides a new idea for the colorimetric detection of LAMP amplicons and can be applied to various fields.
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