Evidence map›Paper›PMID 35498979›Full record

ArticleFood chemistry: X2022

Preparation, chemical structure, and immunostimulatory activity of a water-soluble heteropolysaccharide from

Xiong Gao, Ranhua Zeng, Chi-Tang Ho, Bin Li, Shaodan Chen, Chun Xiao, Huiping Hu, Manjun Cai, Zhongzheng Chen, Yizhen Xie and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Chemical Structure of a Branched α-d-Glucan from the Eggs of Sea UrchinInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Xiong GaoState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Ranhua ZengCollege of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.
Chi-Tang HoDepartment of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, NJ 08901, USA.
Bin LiCollege of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.
Shaodan ChenState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Chun XiaoState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Huiping HuState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Manjun CaiState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Zhongzheng ChenCollege of Food Science, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou 510642, China.
Yizhen XieState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Qingping WuState Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Safety and Health, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, China.
Guangdong Academy of Sciences · CNSouth China Agricultural University · CNInstitute of Microbiology · CNRutgers, The State University of New Jersey · USZhaoqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A water-soluble heteropolysaccharide (SGP2-1) was purified from

Indexed as

1H-1H COSY, 1H-1H correlation spectroscopyAkt, Protein kinase BANOVA, Analysis of varianceCCK-8, Cell counting kit-8D2O, Deuterium oxideDCFH-DA, 2′,7′-Dichlorofluorescein diacetateDEPT, Distortionless enhancement by polarization transferDMEM, Dulbecco’s modified Eagle’s mediumDPBS, Dulbecco’s phosphate-buffered salineELISA, Enzyme-linked immunosorbent assayERK, Extracellular signal-regulated kinaseFT-IR, Fourier transform infrared spectroscopyGC-MS, Gas chromatography-mass spectrometryHeteropolysaccharideHMBC, Heteronuclear multiple bond correlationHPGPC, High-performance gel permeation chromatographyHPLC, High performance liquid chromatographyHSQC, Heteronuclear single quantum correlationIL-6, Interleukin-6Immunomodulatory activityiNOS, Inducible nitric oxide synthaseIκBα, I kappa B alphaJNK, c-Jun N-terminal kinaseLPS, LipopolysaccharidesMAPKs, Mitogen-activated protein kinaseMCP-1, Monocyte chemoattractant protein-1Mw, Weight average molecular weightNF-κB, Nuclear factor-kappa BNMR, Nuclear magnetic resonanceNO, Nitric oxidePI3K, Phosphatidylinositol-3-kinasePMP, 1-Phenyl-3-methyl-5-pyrazoloneRIPA, Radioimmunoprecipitation assayROS, Reactive oxygen speciesRT-PCR, Reverse transcription-polymerase chain reactionStructural characterizationSuillus granulatusTLR2, Toll-like receptor 2TLR4, Toll-like receptor 4TNF-α, Tumor necrosis factor-α

Identifiers

PMID35498979
PMCPMC9039890
OpenAlexW4206177606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.