Evidence map›Paper›PMID 35498938›Full record

ArticleRSC advances2021

Cancer antigen 125 assessment using carbon quantum dots for optical biosensing for the early diagnosis of ovarian cancer.

Walaa E Omer, Mostafa F Abdelbar, Nesma M El-Kemary, Naoki Fukata, Maged A El-Kemary

Abstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Walaa E OmerInstitute of Nanoscience and Nanotechnology, Kafrelsheikh University 33516 Kafr Elsheikh Egypt elkemary@nano.kfs.edu.eg elkemary@yahoo.com.
Mostafa F AbdelbarInstitute of Nanoscience and Nanotechnology, Kafrelsheikh University 33516 Kafr Elsheikh Egypt elkemary@nano.kfs.edu.eg elkemary@yahoo.com.
Nesma M El-KemaryDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Kafrelsheikh University 33516 Kafr Elsheikh Egypt.
Naoki FukataDepartment of Pharmaceutical Microbiology, Faculty of Pharmacy, Kafrelsheikh University 33516 Kafr Elsheikh Egypt.ORCID https://orcid.org/0000-0002-0986-8485
Maged A El-KemaryInstitute of Nanoscience and Nanotechnology, Kafrelsheikh University 33516 Kafr Elsheikh Egypt elkemary@nano.kfs.edu.eg elkemary@yahoo.com.ORCID https://orcid.org/0000-0003-0679-1715

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorometric quantification of biological molecules is a key feature used in many biosensing studies. Fluorescence resonance energy transfer (FRET) using highly fluorescent quantum dots offers highly sensitive detection of the in-proximity wide variety of analyst molecules. In this contribution, we report the use of carbon quantum dots (CDs) for the ultrasensitive optical biosensing of cancer antigen 125 (CA-125) in the early malignant stage. This approach is based on monitoring the quenching of CDs luminescence at 535 nm by CA-125 after excitation at 425 nm and pH 10. The calibration of this method was performed in the concentration range of CA-125 from 0.01 to 129 U ml

Identifiers

PMID35498938
PMCPMC9041374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.