Evidence map›Paper›PMID 35498870›Full record

ReviewRSC advances2020

Structural features, interaction with the gut microbiota and anti-tumor activity of oligosaccharides.

Yulin Wu, Yinning Chen, Yingfang Lu, Huili Hao, Jun Liu, Riming Huang

Abstract readReview
In one paragraph

Review in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yulin WuGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University Guangzhou 510642 China DanielWu@stu.scau.edu.cn luyingfang@stu.scau.edu.cn hhlhaohuili@stu.scau.edu.cn huangriming@scau.edu.cn +86 20 8528 3448 +86 7592388240.
Yinning ChenGuangdong Polytechnic College 526100 Zhaoqing China Yinning_Chen@163.com.
Yingfang LuGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University Guangzhou 510642 China DanielWu@stu.scau.edu.cn luyingfang@stu.scau.edu.cn hhlhaohuili@stu.scau.edu.cn huangriming@scau.edu.cn +86 20 8528 3448 +86 7592388240.
Huili HaoGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University Guangzhou 510642 China DanielWu@stu.scau.edu.cn luyingfang@stu.scau.edu.cn hhlhaohuili@stu.scau.edu.cn huangriming@scau.edu.cn +86 20 8528 3448 +86 7592388240.
Jun LiuLaboratory of Pathogenic Biology, Guangdong Medical University Zhanjiang 524023 China lj2388240@gdmu.edu.cn.
Riming HuangGuangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University Guangzhou 510642 China DanielWu@stu.scau.edu.cn luyingfang@stu.scau.edu.cn hhlhaohuili@stu.scau.edu.cn huangriming@scau.edu.cn +86 20 8528 3448 +86 7592388240.ORCID https://orcid.org/0000-0001-6258-3297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some oligosaccharides are regarded as biological constituents with benefits to human health in an indirect way. They enter the intestinal tract to be fermented by the gut microbiota, causing changes in the abundance and composition of the gut microbiota and producing fermentation products such as short-chain fatty acids (SCFAs). In this review, the structural features and biological activities of eight common natural oligosaccharides were summarized, including human milk oligosaccharides (HMOS), xylo-oligosaccharides (XOS), arabinoxylo-oligosaccharides (AXOS), isomaltooligosaccharides (IMOS), chitin oligosaccharides (NACOS), mannan-oligosaccharides (MOS), galacto-oligosaccharides (GOS) and fructo-oligosaccharides (FOS). Furthermore, XOS were selected to explain the anti-tumor mechanism mediated by gut microbiota. The review aims to reveal primary structural features of natural functional oligosaccharides related to the biological activities and also provide an explanation of the anti-tumor activity of functional oligosaccharides mediated by the gut microbiota.

Identifiers

PMID35498870
PMCPMC9053055

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.