Evidence map›Paper›PMID 35498853›Full record

ArticleRSC advances2020

Exploring the binding mode and thermodynamics of inverse agonists against estrogen-related receptor alpha.

Konda Reddy Karnati, Yixuan Wang, Yongli Du

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Konda Reddy KarnatiDepartment of Chemistry and Forensic Science, Albany State University Albany GA 31705 USA yixuan.wang@asurams.edu.ORCID https://orcid.org/0000-0002-5847-0473
Yixuan WangDepartment of Chemistry and Forensic Science, Albany State University Albany GA 31705 USA yixuan.wang@asurams.edu.ORCID https://orcid.org/0000-0001-9969-2710
Yongli DuSchool of Chemical and Pharmaceutical Engineering, Qilu University of Technology (Shandong Academy of Sciences) Jinan Shandong 250353 China.
Albany State University · USQilu University of Technology · CN

Funding

Understanding Non-covalent Interaction in Carbon Nanotube/Anticancer Drug ConjugaSC3GM105576 · NIGMS · ALBANY STATE UNIVERSITY · PI WANG, YIXUAN · 2014 to 2017
$421k
NIGMS NIH HHS SC3 GM105576
6 · The paper itself

Abstract

Since estrogen-related receptor alpha (ERRα), one of three estrogen-related receptors, displays constitutively active transcriptional activities and important implications in both physiological and pathological processes of breast cancers, ERRα was recently recognized as a new target to fight breast cancers, and regulating the activity of ERRα with inverse agonists has thus become a promising new therapeutic strategy. A few inverse agonists cyclohexylmethyl-(1-

Identifiers

PMID35498853
PMCPMC9053173
OpenAlexW3017817782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.