ArticleRSC advances2020
Covalently functionalized poly(etheretherketone) implants with osteogenic growth peptide (OGP) to improve osteogenesis activity.
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Investigating the Effects of Charge on the Release Kinetics of Charge-Modified Peptides from Gelatin Microparticles.Cell biomaterials · 2026Article
- Endowing implants surface with enhanced vascularization and osseointegration via presenting triple-functional peptides.Journal of orthopaedic translation · 2025Article
- Peptide-Functionalized Nanomedicine: Advancements in Drug Delivery, Diagnostics, and Biomedical Applications.Molecules (Basel, Switzerland) · 2025Review
- A pH-Responsive Polyetheretherketone Implant Modified with a Core-Shell Metal-Organic Framework to Promote Antibacterial and Osseointegration Abilities.Biomaterials research · 2025Article
- Polyetheretherketone Double Functionalization with Bioactive Peptides Improves Human Osteoblast Response.Biomimetics (Basel, Switzerland) · 2024Article
- Enhanced vascularization and osseointegration under osteoporotic conditions through functional peptide coating on implant surfaces.Materials today. Bio · 2024Article
- Alendronate as Bioactive Coating on Titanium Surfaces: An Investigation of CaP-Alendronate Interactions.Materials (Basel, Switzerland) · 2024Article
- Engineering tunable dual peptide hybrid coatings promote osseointegration of implants.Materials today. Bio · 2024Article
- Using dynamic biomaterials to study the temporal role of bioactive peptides during osteogenesis.Biomaterials advances · 2024Article
- Chemically heparinized PEEKRSC advances · 2024Article
- Multifunctional surface of the nano-morphic PEEK implant with enhanced angiogenic, osteogenic and antibacterial properties.Regenerative biomaterials · 2024Article
- Construction of multifunctional coating with cationic amino acid-coupled peptides for osseointegration of implants.Materials today. Bio · 2023Article
- Strategies for the Covalent Anchoring of a BMP-2-Mimetic Peptide to PEEK Surface for Bone Tissue Engineering.Materials (Basel, Switzerland) · 2023Article
- Bioactive PEEK: Surface Enrichment of Vitronectin-Derived Adhesive Peptides.Biomolecules · 2023Article
- State-of-the-art polyetheretherketone three-dimensional printing and multifunctional modification for dental implants.Frontiers in bioengineering and biotechnology · 2023Review
- Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy.Bioactive materials · 2022Article
- Selected Spectroscopic Techniques for Surface Analysis of Dental Materials: A Narrative Review.Materials (Basel, Switzerland) · 2021Review
- Porous polyetheretherketone microcarriers fabricated via hydroxylation together with cell-derived mineralized extracellular matrix coatings promote cell expansion and bone regeneration.Regenerative biomaterials · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyetheretherketone (PEEK), as the most promising implant material for orthopedics and dental applications, has bone-like stiffness, excellent fatigue resistance, X-ray transparency, and near absence of immune toxicity. However, due to biological inertness, its bone conduction and bone ingrowth performance is limited. The surface modification of PEEK is an option to overcome these shortcomings and retain most of its favorable properties, especially when excellent osseointegration is desired. In this study, a simple reaction procedure was employed to bind the osteogenic growth peptide (OGP) on the surface of PEEK materials by covalent chemical grafting to construct a bioactive interface. The PEEK surface was activated by
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.