ArticleRSC advances2020
The synthesis of a DHAD/ZnAlTi-LDH composite with advanced UV blocking and antibacterial activity for skin protection.
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Zwitterionic chitosan-modified amorphous ZnCuAl-LDH eye drops for efficient treatment of bacterial keratitis.Materials today. Bio · 2025Article
- Layered double hydroxides for regenerative nanomedicine and tissue engineering: recent advances and future perspectives.Journal of nanobiotechnology · 2025Review
- Synthesis and anti-proliferative activity of dehydroabietinol derivatives bearing a triazole moiety.RSC medicinal chemistry · 2023Article
- Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid.Toxins · 2022Review
- Synthesis, antifungal activity and 3D-QSAR study of novel acyl thiourea compounds containing gem-dimethylcyclopropane ring.Molecular diversity · 2022Article
- Visible-Light-Active CuOACS omega · 2021Article
- Synthesis, 3D-QSAR and Molecular Docking Study of Nopol-Based 1,2,4-Triazole-Thioether Compounds as Potential Antifungal Agents.Frontiers in chemistry · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin wounds are particularly vulnerable and susceptible to bacterial infection. Unfortunately, the abuse of antibiotics has resulted in the emergence of a number of multidrug-resistant bacteria in the past few decades. Moreover, secondary damage of the fragile new tissue around the wound caused by high-energy ultraviolet (UV) radiation has been rarely noticed. To address these problems, herein, we present an alternative strategy to overcome drug-resistant bacteria and UV damage by taking advantage of dehydroabietic acid derivatives (DHADs) and layered double hydroxides (LDHs). DHAD, synthesized from dehydroabietic acid (DHA) through a series of reactions, was assembled with ZnAlTi-LDH to obtain a DHAD/ZnAlTi-LDH composite. The results showed that DHAD/ZnAlTi-LDH has a prominent reactive oxygen species (ROS) production capacity, and both Gram-negative and positive bacteria can be killed under visible light irradiation. At the same time, it can effectively shield the skin from UV rays.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.