Evidence map›Paper›PMID 35498438›Full record

ArticleFrontiers in endocrinology2022

The Predictive Value of Serum Calcium on Heart Rate Variability and Cardiac Function in Type 2 Diabetes Patients.

Junyi Wang, Zihui Xu, Kang Lv, Yingchun Ye, Deng Luo, Li Wan, Fen Zhou, Ailin Yu, Shuo Wang, Jingcheng Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Junyi WangDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Zihui XuDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Kang LvShenzhen University, College of Big Data and Internet, Shenzhen, China.
Yingchun YeDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Deng LuoDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Li WanDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Fen ZhouDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Ailin YuDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Shuo WangDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Jingcheng LiuDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Ling GaoDepartment of Endocrinology & Metabolism, Renmin Hospital of Wuhan University, Wuhan, China.
Wuhan University · CNRenmin Hospital of Wuhan University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular autonomic neuropathy (CAN) is common in patients with type 2 diabetes mellitus (T2DM), mainly presented as decreased heart rate variability (HRV) which often leads to cardiac death. However, HRV measurement is not convenient in most clinics. Therefore, identifying high-risk patients for CAN in diabetes with easier measurements is crucial for the early intervention and prevention of catastrophic consequences. Methods: In this cross-sectional study, 675 T2DM patients with normocalcemia were selected. Of these, they were divided into two groups: normal HRV group (n = 425, 100 ms≤ SDNN ≤180 ms) Results: In this study, declines in HRV were present in 37.0% of T2DM patients. Significant differences in albumin-adjusted serum calcium levels (CaA) (8.86 ± 0.27 Conclusions: Declined HRV is associated with a lower CaA level and worse cardiac function. The serum calcium level can be used for risk evaluation of declined HRV in T2DM patients even within the normocalcemic range.

Indexed as

Diabetes Mellitus, Type 2CalciumCross-Sectional StudiesHeart RateHumansROC CurveCalciumcalciumcardiovascular autonomic neuropathyheart rate variabilitySDNNtype 2 diabetes mellitus

Identifiers

PMID35498438
PMCPMC9047897
OpenAlexW4224011451

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.