Evidence map›Paper›PMID 35498436›Full record

ArticleFrontiers in endocrinology2022

Nuclear Progesterone Receptor Expressed by the Cortical Thymic Epithelial Cells Dictates Thymus Involution in Murine Pregnancy.

Soo Hyun Ahn, Sean L Nguyen, Tae Hoon Kim, Jae-Wook Jeong, Ripla Arora, John P Lydon, Margaret G Petroff

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  5. Frontiers in immunology · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Soo Hyun AhnDepartment of Pathobiology Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States.
Sean L NguyenInstitute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States.
Tae Hoon KimDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI, United States.
Jae-Wook JeongDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI, United States.
Ripla AroraDepartment of Obstetrics, Gynecology, and Reproductive Biology, Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, United States.
John P LydonDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, United States.
Margaret G PetroffDepartment of Pathobiology Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States.
Michigan State University · USBaylor College of Medicine · US

Funding

Maternal Central Immune Tolerance in ReproductionR01HD100832 · NICHD · MICHIGAN STATE UNIVERSITY · PI PETROFF, MARGARET G · 2020 to 2024
$2.0M
Endocrine regulation of maternal immunity in pregnancyR21AI142173 · NIAID · MICHIGAN STATE UNIVERSITY · PI PETROFF, MARGARET G · 2020 to 2021
$430k
Maternal Central Immune Tolerance to the Fetal-Placental UnitR21HD062879 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI PETROFF, MARGARET G · 2010 to 2011
$405k
NIAID NIH HHS R21 AI142173NICHD NIH HHS R01 HD100832NICHD NIH HHS R21 HD062879
6 · The paper itself

Abstract

Progesterone is a gonadal pro-gestational hormone that is absolutely necessary for the success of pregnancy. Most notable actions of progesterone are observed in the female reproductive organs, the uterus and the ovary. Acting through the nuclear progesterone receptor (PGR), progesterone prepares the endometrium for implantation of the embryo. Interestingly, the maternal thymus also is a known expressor of

Indexed as

ProgesteroneReceptors, ProgesteroneAnimalsEpithelial CellsFemaleMiceMice, TransgenicPregnancyUterusProgesteroneReceptors, Progesteronefertilityinvolutionpregnancyprogesterone receptor (PGR)thymus

Identifiers

PMID35498436
PMCPMC9046655
OpenAlexW4224031404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.