Evidence map›Paper›PMID 35498295›Full record

ArticleRSC advances2020

Unveiling the anti-cancer mechanism for half-sandwich and cyclometalated Ir(iii)-based complexes with functionalized α-lipoic acid.

Meng-Meng Wang, Xu-Ling Xue, Xi-Xi Sheng, Yan Su, Ya-Qiong Kong, Yong Qian, Jian-Chun Bao, Zhi Su, Hong-Ke Liu

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 26 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Meng-Meng WangJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Xu-Ling XueJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Xi-Xi ShengJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Yan SuJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Ya-Qiong KongJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Yong QianJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.
Jian-Chun BaoJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.ORCID https://orcid.org/0000-0003-2818-6786
Zhi SuJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.ORCID https://orcid.org/0000-0003-1690-527X
Hong-Ke LiuJiangsu Collaborative Innovation Center of Biomedical Functional Materials, College of Chemistry and Materials Science, Nanjing Normal University Nanjing 210023 China zhisu@njnu.edu.cn liuhongke@njnu.edu.cn.ORCID https://orcid.org/0000-0002-0968-6518
Nanjing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha lipoic acid (LA) is a natural compound and coenzyme with sufficient safety information for serving as a promising anticancer agent. To further clarify the mechanism of action (MoA), two Ir(iii) complexes with the functionalized α-lipoic acid (N

Identifiers

PMID35498295
PMCPMC9049077
OpenAlexW3003847669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.