Evidence map›Paper›PMID 35498269›Full record

ArticleHardwareX2020

A low-cost and customizable alternative for commercial implantable cannula for intracerebral administration in mice.

Rogneda B Kazanskaya, Alexander V Lopachev, Tatiana N Fedorova, Raul R Gainetdinov, Anna B Volnova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HardwareX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rogneda B KazanskayaBiological Department, Saint Petersburg State University, Universitetskaya Emb. 7/9, 199034 St Petersburg, Russia.
Alexander V LopachevResearch Center of Neurology, Volokolamskoye shosse 80, 125367 Moscow, Russia.
Tatiana N FedorovaResearch Center of Neurology, Volokolamskoye shosse 80, 125367 Moscow, Russia.
Raul R GainetdinovInstitute of Translational Biomedicine, Saint Petersburg State University, Universitetskaya Emb. 7/9, 199034 St Petersburg, Russia.
Anna B VolnovaBiological Department, Saint Petersburg State University, Universitetskaya Emb. 7/9, 199034 St Petersburg, Russia.
St Petersburg University · RUResearch Center of Neurology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotaxic intracerebral cannula implantation for neuroactive agent administration is a wide-spread method for chronic experiments requiring bypassing the blood-brain barrier in rodents. However, commercially available cannula are bulky and may interfere with animal movement or lead to their dislodging during grooming. As the number of cannula needed in one experiment, and the accompanying costs can be high, it is in the interest of researchers to produce them on their own. Custom cannula manufacturing also offers the flexibility of different cannula lengths, which is required for agent delivery to various brain structures. In this article we present a protocol for making guide cannula along with the accompanying systems required for injection, which are small, cost-effective, light, easy to make, reusable, and can be made from easily procured materials.

Indexed as

Drug testingIntracerebral cannulaStereotaxic surgery

Identifiers

PMID35498269
PMCPMC9041169
OpenAlexW3031794074

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.