ArticleHardwareX2020
Standardized tensile testing of soft tissue using a 3D printed clamping system.
Article in HardwareX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shape or size matters? Towards standard reporting of tensile testing parameters for human soft tissues: systematic review and finite element analysis.Frontiers in bioengineering and biotechnology · 2024Pooled it
- Evaluation of a novel strap fixation method for biomechanical testing of sheep Achilles tendons.Archives of orthopaedic and trauma surgery · 2026Article
- Article
- Experimental characterization of the non-linear viscoelastic properties of human female perineal tissue.Scientific reports · 2025Article
- Unlocking the secrets of aortic pseudoaneurysms - exploring tensile testing of prostheses, anastomoses, and native vessels in the thoracic aorta: A clinical-engineering correlation.Journal of applied biomedicine · 2025Article
- Crosado embalming related alterations in the morpho-mechanics of collagen rich tissues.Scientific reports · 2025Article
- Article
- Effects of Two Decellularization Protocols on the Mechanical Behavior and Structural Properties of the Human Urethra.International journal of molecular sciences · 2024Article
- On a potential morpho-mechanical link between the gluteus maximus muscle and pelvic floor tissues.Scientific reports · 2023Article
- Development of a 3D Printed Double-Acting Linear Pneumatic Actuator for the Tendon Gripping.Polymers · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomechanical testing of soft tissues forms the backbone in the experimental validation of tissue engineering and for modelling purposes. The standardized testing of soft tissues requires different experimental protocols and fixtures compared to hard tissues or non-biological materials due to their characteristics. Some of the most commonly-used clamping methods for soft tissue testing affect the tissues' mechanical properties as chemicals are involved to decelerate degradation and autolysis. Moreover, they are unsuitable for standardized and high-throughput testing. Material slippage is also a recurrent unwanted influence on the testing routine with impact on measurement validity. Addressing these issues, this protocol presents a clamping system for simplified testing of biological soft tissues with all necessary components manufactured utilizing 3D printing technology. Templates allow trimming the samples into standardized shapes and sizes while preparation tables facilitate clamping in a fixed distance. The key parts of the system are clamps with a pyramid design, which allow the mounting of biological soft tissues before transferring it into the testing device and minimize material slippage during tensile testing. Flexible holder arms are used to transfer samples from preparation tables into the testing device and simplify positioning. Mechanical testing itself is performed with digital image correlation for precise strain measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.