ReviewKidney medicine2022
Survival of Older Patients With Advanced CKD Managed Without Dialysis: A Narrative Review.
Review in Kidney medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- A Risk-Oriented and Explainable Hierarchical AI Framework for Chronic Kidney Disease Classification.Diagnostics (Basel, Switzerland) · 2026Article
- Trends in chronic kidney disease-related mortality in older adults in the United States from 1999 to 2020: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- Outcomes of patients in a pre-dialysis clinic and implications for shared decision making.Clinical kidney journal · 2025Article
- Management of Elderly Patients with Chronic Kidney Disease.Yonsei medical journal · 2025Review
- The trajectory of functional status of patients with kidney failure choosing conservative kidney management.International urology and nephrology · 2025Article
- Clinical characteristics and outcomes of patients on haemodialysis at Jimma medical center, Ethiopia: a 7-Year review.BMC nephrology · 2024Article
- Review
- Shared decision making in elderly patients with kidney failure.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Review
- Conservative Kidney Management Practice Patterns and Resources in the United States: A Cross-Sectional Analysis of CKDopps (Chronic Kidney Disease Outcomes and Practice Patterns Study) Data.Kidney medicine · 2023Article
- Chronic kidney disease in the elderly and frail patient: perspectives with opinions and comments.Journal of nephrology · 2023Article
- Development and Acceptability of a Kidney Therapy Decision Aid for Patients Aged 75 Years and Older: A Design-Based Research Involving Patients, Caregivers, and a Multidisciplinary Team.Kidney medicine · 2023Article
- A review of supportive care for older people with advanced chronic kidney disease.Clinical kidney journal · 2023Review
- Conservative Kidney Management in Kidney Transplant Populations.Seminars in nephrology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shared decision making is important when deciding the appropriateness of dialysis for any individual, particularly for older patients with advanced chronic kidney disease who have high mortality. Emerging evidence suggests that patients with advanced age, high comorbidity burden, and poor functional status may not have any survival advantage on dialysis compared with those on a conservative kidney management pathway. The purpose of this narrative review is to summarize the existing studies on the survival of older patients with stage 4 or 5 chronic kidney disease managed with or without dialysis and to evaluate the factors that may influence mortality in an effort to assist clinicians with shared decision making. Median survival estimates of conservative kidney management patients are widely varied, ranging from 1-45 months with 1-year survival rates of 29%-82%, making it challenging to provide consistent advice to patients. In existing cohort studies, the selected group of patients on dialysis generally survives longer than the conservative kidney management cohort. However, in patients with advanced age (aged ≥80 years), high comorbidity burden, and poor functional status, the survival benefit conferred by dialysis is no longer present. There is an overall paucity of data, and the variability in outcomes reflect the heterogeneity of the existing studies; further prospective studies are urgently needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.