Evidence map›Paper›PMID 35498136›Full record

ArticleOxidative medicine and cellular longevity2022

Screening of lncRNA-miRNA-mRNA Coexpression Regulatory Networks Involved in Acute Traumatic Coagulation Dysfunction Based on CTD, GeneCards, and PharmGKB Databases.

Yong Luo, Yong Fu, Taifa Tan, Jun Hu, Fang Li, Zhanchen Liao, Jian Peng

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Circadian clock regulation of hemostasis: a systematic review of molecular pathways.Research and practice in thrombosis and haemostasis · 2026
    Pooled it
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  10. Journal of pain research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yong LuoHengyang Medical School, University of South China, Hengyang 421001, China.ORCID https://orcid.org/0000-0002-7367-3252
Yong FuTrauma Orthopedic Department & Trauma Centre, The Second Affiliated Hospital of the University of South China, Hengyang 421000, China.
Taifa TanRadiology Department & Trauma Centre, The Second Affiliated Hospital of the University of South China, Hengyang 421000, China.
Jun HuCardiothoracic Surgery & Trauma Centre, The Second Affiliated Hospital of the University of South China, Hengyang 421000, China.
Fang LiCritical Care Medicine & Trauma Centre, The Second Affiliated Hospital of the University of South China, Hengyang 421000, China.
Zhanchen LiaoHengyang Medical School, University of South China, Hengyang 421001, China.
Jian PengDepartment of General Surgery, Xiangya Hospital, Central South University, Changsha 410008 P. R., China.
University of South China · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Competitive endogenous RNA (ceRNA) networks play crucial roles in multiple biological processes and development of diseases. They might serve as diagnostic and prognosis markers as well as therapeutic targets. The purpose of this study was to identify a novel ceRNA network involving KCNQ1OT1, hsa-miR-24-3p, and VWF in acute traumatic coagulopathy (ATC) based on databases search. We searched the CTD, GeneCards, and PharmGKB databases for ATC-related target genes using Coagulopathy as a keyword. Upstream miRNAs and lncRNAs of the candidate target VWF were then explored using the miRWalk, microT, TargetScan, RNA22 and Tarbase, and DIANA-LncBase and Starbase databases, respectively. A KCNQ1OT1-hsa-miR-24-3p-VWF ceRNA network was constructed by

Indexed as

MicroRNAsRNA, Long NoncodingAnimalsHumansRatsRNA, Messengervon Willebrand FactorMicroRNAsMIRN24 microRNA, ratRNA, Long NoncodingRNA, Messengervon Willebrand Factor

Identifiers

PMID35498136
PMCPMC9042625
OpenAlexW4224295508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.