Evidence map›Paper›PMID 35498014›Full record

ArticleFrontiers in cardiovascular medicine2022

Clinical Impact and Prognostic Role of Triglyceride to High-Density Lipoprotein Cholesterol Ratio in Patients With Chronic Coronary Syndromes at Very High Risk: Insights From the START Study.

Leonardo De Luca, Pier Luigi Temporelli, Furio Colivicchi, Lucio Gonzini, Maria Luisa Fasano, Massimo Pantaleoni, Gabriella Greco, Fabrizio Oliva, Domenico Gabrielli, Michele Massimo Gulizia

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leonardo De LucaDepartment of Cardiosciences, Division of Cardiology, S. Camillo-Forlanini, Roma, Italy.
Pier Luigi TemporelliDivision of Cardiology, Istituti Clinici Scientifici Maugeri, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Gattico-Veruno, Italy.
Furio ColivicchiDivision of Cardiology, S. Filippo Neri Hospital, Roma, Italy.
Lucio GonziniANMCO Research Center, Firenze, Italy.
Maria Luisa FasanoDivision of Cardiology, Cardiac Rehabilitation Unit, S. Carlo Hospital, Potenza, Italy.
Massimo PantaleoniDivision of Cardiology, Santa Maria Nuova Hospital, Reggio Emilia, Italy.
Gabriella GrecoDivision of Cardiology, Santo Spirito Hospital, Roma, Italy.
Fabrizio OlivaCardiovascular Department, Division of Cardiology, "A. De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy.
Domenico GabrielliDepartment of Cardiosciences, Division of Cardiology, S. Camillo-Forlanini, Roma, Italy.
Michele Massimo GuliziaDivision of Cardiology, Garibaldi-Nesima Hospital, Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several studies have reported that the combination of high TG and low HDL-C, as simplified by the TG/HDL-C ratio, was a predictor of cardiovascular disease independent of LDL-C level. Nevertheless, poor data are available on the predictive role of TG/HDL-C ratio in very high risk (VHR) patients with chronic coronary syndromes (CCS). Methods: Using the data from the STable Coronary Artery Diseases RegisTry (START) study, an Italian nationwide registry, we assessed the association between the TG/HDL-C ratio and baseline clinical characteristics, pharmacological treatment, and major adverse cardio-cerebrovascular events (MACCE) at 1 year in a large cohort of CCS patients at VHR. Results: VHR patients with both TG and HDL-C levels available were grouped in tertiles of TG/HDL-C ratio: low (TG/HDL-C ratio <2, Conclusions: In the present large, nationwide cohort of CCS patients at VHR a high TG/HD ratio did not emerge as independent predictor of MACCE at 1 year. Further studies with a longer follow-up are needed to better define the prognostic role of TG/HDL ratio in CCS.

Indexed as

chronic coronary syndromehypercholesterolemiaLDL-Cmanagementstatintreatment

Identifiers

PMID35498014
PMCPMC9043517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.