Evidence map›Paper›PMID 35497850›Full record

ArticleRSC advances2020

A simple and rapid colorimetric detection of serum lncRNA biomarkers for diagnosis of pancreatic cancer.

Ut Kei Lou, Chi Hin Wong, Yangchao Chen

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ut Kei LouSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong Shatin NT Hong Kong yangchaochen@cuhk.edu.hk +852 26035123 +852 39431100.
Chi Hin WongSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong Shatin NT Hong Kong yangchaochen@cuhk.edu.hk +852 26035123 +852 39431100.
Yangchao ChenSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong Shatin NT Hong Kong yangchaochen@cuhk.edu.hk +852 26035123 +852 39431100.ORCID https://orcid.org/0000-0002-0249-3414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A colorimetric assay is developed for detection of lncRNA HOTTIP by one-step reverse transcription-loop-mediated isothermal amplification (RT-LAMP) coupled with positively-charged gold nanoparticles ((+)AuNP) for diagnosis of pancreatic cancer. This assay allows simple, rapid, and sensitive quantification of lncRNA down to 50 copies.

Identifiers

PMID35497850
PMCPMC9049936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.