Evidence map›Paper›PMID 35497795›Full record

ArticleKidney international reports2022

Incidence, Risk Factors and Outcomes of Kidney and Liver Cyst Infection in Kidney Transplant Recipient With ADPKD.

Charles Ronsin, Anis Chaba, Ondrej Suchanek, Jean-Philippe Coindre, Clarisse Kerleau, Claire Garandeau, Aurélie Houzet, Diego Cantarovich, Jacques Dantal, Gilles Blancho and 3 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Liver transplantation indications and strategies in polycystic liver disease: A European survey.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
  2. Article
  3. Review
  4. Liver Cyst Infection Outcomes in Patients With ADPKD.Kidney international reports · 2026
    Article
  5. Review
  6. Article
  7. Nephrectomy in autosomal dominant polycystic kidney disease: a consensus statement of the ERA Genes & Kidney Working Group.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Performance of [Diagnostics (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Charles RonsinDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Anis ChabaParis University, Paris, France.
Ondrej SuchanekCambridge University Hospitals NHS, Foundation Trust, NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
Jean-Philippe CoindreDepartment of Nephrology, Le Mans Hospital, Le Mans, France.
Clarisse KerleauCentre de Recherche en Transplantation et Immunologie UMR 1064, Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Nantes, Nantes, France.
Claire GarandeauDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Aurélie HouzetDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Diego CantarovichDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Jacques DantalDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Gilles BlanchoDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Magali GiralDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Grégoire Couvrat-DesvergnesDepartment of Nephrology, Dialysis and Transplantation, Departmental Hospital of Vendée, La Roche-sur-Yon, France.
Simon VilleDepartment of Nephrology and Immunology, Center Hospitalier Universitaire de Nantes, Nantes, France.
Center for Research in Transplantation and Translational ImmunologyCentre d'Investigation Clinique de Nantes · FRCentre Hospitalier du Mans · FRCentre Hospitalier Universitaire de Nantes · FRInserm · FRInstitut de Transplantation Urologie en Nephrologie · FRNIHR Cambridge Biomedical Research CentreRoche (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cyst infection is a known complication of autosomal dominant polycystic kidney disease (ADPKD). Here, we describe incidence, risk factors, clinical presentation, and outcomes of cyst infection in kidney transplant recipient. Methods: We conducted a single-center retrospective cohort study of patients with ADPKD with renal allografts between January 1, 2009, and October 31, 2020. Cyst infection diagnosis was based on previously described clinical and radiological criteria, using positron emission tomography when available. Results: A total of 296 patients with ADPKD with renal allografts were included, and 21 patients experienced 22 episodes of cyst infection over a median follow-up of 4 (2-7) years. The cumulative incidence rate was 3% at 1 year, 6 % at 5 years, and 12% at 10 years after transplantation. In multivariate analysis, history of cyst infection before transplantation was the only significant risk factor identified to predict the occurrence of cyst infection after kidney transplantation (hazard ratio [HR] 3.47, 95% CI 1.29-9.31). The clinical presentation at diagnosis of cyst infection included isolated fever in 5 (23%) episodes, acute kidney injury in 12 (55%), and severe sepsis/septic shock in 3 (14%) episodes. Among the 16 (73%) episodes with culture positivity, Conclusion: Incidence of cyst infection in ADPKD after kidney transplantation is low, history of cyst infection representing the main risk factor.

Indexed as

autosomal dominant polycystic kidney diseasecyst infectionincidencekidney transplantationrisk factors

Identifiers

PMID35497795
PMCPMC9039903
OpenAlexW4210336349

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.