ArticleThe World Allergy Organization journal2022
The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update.
Article in The World Allergy Organization journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
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Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiology, economic, and humanistic burden of hereditary angioedema: a systematic review.Orphanet journal of rare diseases · 2024Pooled it
- On-demand treatment of icatibant in a patient of hereditary angioedema with KNG1 mutation.Genes & diseases · 2027Article
- Transient C1-Inhibitor Functional Abnormalities During Acute Idiopathic Pancreatitis: A Diagnostic Challenge in Hereditary Angioedema Evaluation.Digestive diseases and sciences · 2026Article
- Article
- Berotralstat Tolerability and Effectiveness in Hereditary Angioedema: Berolife Study Results.Clinical and translational allergy · 2026Article
- Switching Long-Term Prophylaxis to Donidalorsen for Hereditary Angioedema: 1-Year OASISplus Results.Allergy · 2026Article
- Physician Awareness of Hereditary Angioedema: A Cross-Sectional Survey with Emphasis on Medication-Related Triggers.Journal of clinical medicine · 2026Article
- Toward equitable and evidence-based care in Hereditary Angioedema: Time for inclusive global guidelines.The World Allergy Organization journal · 2026Article
- The Neglected Older Adults in Hereditary Angioedema: Insights From the ITACA Registry.Clinical and translational allergy · 2026Article
- Advances in hereditary angioedema in the modern treatment era in China: a focus on diagnosis, treatment, and prognosis.Orphanet journal of rare diseases · 2026Review
- Is hereditary angioedema associated with deficits in emotion regulation? A quantitative study in adult patients.Orphanet journal of rare diseases · 2026Article
- Hereditary angioedema: on-demand treatment and long-term prophylaxis-a global reality.Clinical and experimental immunology · 2026Review
- Hereditary angioedema care across selected health systems in the Balkan Peninsula area: policy gaps, practice variation, and actionable recommendations.Frontiers in allergy · 2026Review
- A Rare Case of Hereditary Angioedema in a 7-Year-Old Girl: Presentation, Diagnosis, and Bridging the Management Gap.Case reports in medicine · 2026Article
- The Chronic Angioedema Registry: what the first 2 years since the implementation of the global registry have taught us.Frontiers in allergy · 2026Article
- Association Between the Angioedema Control Test and Attack Frequency in Hereditary Angioedema.Clinical and translational allergy · 2026Article
- Transmission of F12-related hereditary angioedema through a sperm donor.Frontiers in immunology · 2026Article
- Case Report: Hereditary Angioedema Accompanied by Chronic Spontaneous Urticaria.Clinical, cosmetic and investigational dermatology · 2026Article
- Acquired angioedema due to C1 inhibitor deficiency: real-world clinical characteristics and treatment outcomes.Frontiers in immunology · 2026Article
- Hereditary angioedema: A national investigation of associated comorbidities and surgical procedures.The World Allergy Organization journal · 2025Article
Corrections and comments
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Authors and funding
59 authors.
Funding
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Abstract
Hereditary Angioedema (HAE) is a rare and disabling disease for which early diagnosis and effective therapy are critical. This revision and update of the global WAO/EAACI guideline on the diagnosis and management of HAE provides up-to-date guidance for the management of HAE. For this update and revision of the guideline, an international panel of experts reviewed the existing evidence, developed 28 recommendations, and established consensus by an online DELPHI process. The goal of these recommendations and guideline is to help physicians and their patients in making rational decisions in the management of HAE with deficient C1-inhibitor (type 1) and HAE with dysfunctional C1-inhibitor (type 2), by providing guidance on common and important clinical issues, such as: 1) How should HAE be diagnosed? 2) When should HAE patients receive prophylactic on top of on-demand treatment and what treatments should be used? 3) What are the goals of treatment? 4) Should HAE management be different for special HAE patient groups such as children or pregnant/breast feeding women? 5) How should HAE patients monitor their disease activity, impact, and control? It is also the intention of this guideline to help establish global standards for the management of HAE and to encourage and facilitate the use of recommended diagnostics and therapies for all patients.
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