Evidence map›Paper›PMID 35497642›Full record

ArticleAIChE journal. American Institute of Chemical Engineers2021

Response of Astrocytes to Blood Exposure due to Shunt Insertion

Mira Zaranek, Rooshan Arshad, Kevin Zheng, Carolyn A Harris

Abstract read
In one paragraph

Article in AIChE journal. American Institute of Chemical Engineers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Quantitative and qualitative investigation of shunt failure in anFrontiers in bioengineering and biotechnology · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mira ZaranekWayne State University Dept. of Chemical Engineering and Materials Science, 6135 Woodward Avenue, Detroit, MI 48202.
Rooshan ArshadWayne State University Dept. of Chemical Engineering and Materials Science, 6135 Woodward Avenue, Detroit, MI 48202.
Kevin ZhengWayne State University Dept. of Chemical Engineering and Materials Science, 6135 Woodward Avenue, Detroit, MI 48202.
Carolyn A HarrisWayne State University Dept. of Chemical Engineering and Materials Science, 6135 Woodward Avenue, Detroit, MI 48202.

Funding

Investigating the source and the action behind shunt obstruction in the treatment of pediatric hydrocephalusR01NS094570 · NINDS · WAYNE STATE UNIVERSITY · PI Carolyn A Harris · 2016 to 2026
$4.2M
NINDS NIH HHS R01 NS094570
6 · The paper itself

Abstract

The breakdown of the ventricular zone (VZ) with the presence of blood in cerebrospinal fluid (CSF) has been shown to increase shunt catheter obstruction in the treatment of hydrocephalus, but the mechanisms by which this occurs are generally unknown. Using a custom-built incubation chamber, we immunofluorescently assayed cell attachment and morphology on shunt catheters with and without blood after 14 days. Samples exposed to blood showed significantly increased cell attachment (average total cell count 392.0±317.1 versus control of 94.7±44.5,

Indexed as

Blood Brain BarrierHemorrhagePosthemorrhagic HydrocephalusVentricular Catheter

Identifiers

PMID35497642
PMCPMC9049769

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.