Evidence map›Paper›PMID 35497498›Full record

ArticleCell reports methods2022

BTB

Lena Nitsch, Patrizia Jensen, Hojong Yoon, Jonas Koeppel, Shourya Sonkar Roy Burman, Eric Sebastian Fischer, Claudia Scholl, Stefan Fröhling, Mikołaj Słabicki

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Lena NitschDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Patrizia JensenDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Hojong YoonBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Jonas KoeppelDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Shourya Sonkar Roy BurmanDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Eric Sebastian FischerDepartment of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Claudia SchollDivision of Applied Functional Genomics, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Stefan FröhlingDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Mikołaj SłabickiDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany.
Dana-Farber Cancer Institute · USHeidelberg University · DENational Center for Tumor Diseases · DEGerman Cancer Research Center · DEWellcome Sanger Institute · GB

Funding

Expanding pharmacological modalities for targeted cancer therapyK00CA253754 · NCI · BROAD INSTITUTE, INC. · PI YOON, HOJONG · 2021 to 2023
$292k
NCI NIH HHS K00 CA253754
6 · The paper itself

Abstract

Here, we characterize the BTB domain of the transcription factor BCL6 (BTB

Indexed as

Proto-Oncogene Proteins c-bcl-6Epidermal Growth FactorErbB ReceptorsGene Expression RegulationHumansPhosphorylationProtein MultimerizationSignal TransductionBCL6 protein, humanEpidermal Growth FactorErbB ReceptorsProto-Oncogene Proteins c-bcl-6BI-3802BI-3812BTB domainBTB switchpolymerization switchprotein polymerizationreversibility

Identifiers

PMID35497498
PMCPMC9046236
OpenAlexW4224003627

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.