Evidence map›Paper›PMID 35497493›Full record

ArticleCell reports methods2022

AI-enabled

Bryan He, Syed Bukhari, Edward Fox, Abubakar Abid, Jeanne Shen, Claudia Kawas, Maria Corrada, Thomas Montine, James Zou

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  5. Article
  6. Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  7. Article
  8. Article
  9. PNAS nexus · 2023
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bryan HeDepartment of Computer Science, Stanford University, Stanford, CA 94305, USA.
Syed BukhariDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Edward FoxDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Abubakar AbidDepartment of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
Jeanne ShenDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Claudia KawasDepartment of Neurology, University of California, Irvine, Irvine, CA 92697, USA.
Maria CorradaDepartment of Neurology, University of California, Irvine, Irvine, CA 92697, USA.
Thomas MontineDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
James ZouDepartment of Computer Science, Stanford University, Stanford, CA 94305, USA.
Stanford University · USUniversity of California, Irvine · USChan Zuckerberg Initiative (United States) · US

Funding

Diversity Supplement to R01AG021055; Clinical, Imaging, and Pathological Studies in the Oldest Old: The 90+ StudyR01AG021055 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CORRADA, MARIA, KAWAS, CLAUDIA H. · 2002 to 2024
$36.9M
The Alzheimer's Disease Research Center at the University of California, IrvineP30AG066519 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal M. Glover · 2020 to 2026
$27.9M
Center for Sub-Cellular GenomicsRM1HG010023 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H, KIM, JUNHYONG · 2018 to 2022
$11.0M
Stanford Medicine Center for Longevity and Healthy Aging Research Education CoreP30AG059307 · NIA · STANFORD UNIVERSITY · PI ZOU, JAMES · 2018 to 2025
$4.9M
Neuropathologic substrates for motor and cognitive impairment in three existing cohort studies of Alzheimer's disease and related dementiasUF1AG057707 · NIA · STANFORD UNIVERSITY · PI MONTINE, THOMAS J, WHITE, LON RAY · 2017 to 2017
$3.9M
Identifying the Genetic Etiology of Neuropathology for Alzheimer Disease and Related DementiasR01AG062695 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BEECHAM, GARY WAYNE, MONTINE, THOMAS J · 2019 to 2023
$3.8M
NHGRI NIH HHS RM1 HG010023NIA NIH HHS P30 AG059307NIA NIH HHS P30 AG066519NIA NIH HHS R01 AG021055NIA NIH HHS R01 AG062695NIA NIH HHS UF1 AG057707
6 · The paper itself

Abstract

We develop a deep learning approach,

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesBrainHumansImmunohistochemistryNeurofibrillary TanglesPlaque, AmyloidAmyloid beta-PeptidesAlzheimer's diseaseamyloid plaquedeep learningimmunohistochemistrymachine learningneuritic plaqueneurofibrillary tangle

Identifiers

PMID35497493
PMCPMC9046239
OpenAlexW4220727067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.