Evidence map›Paper›PMID 35497489›Full record

ArticleDrug and alcohol dependence reports2022

Impact of reduced restrictions on buprenorphine prescribing during COVID-19 among patients in a community-based treatment program.

Kathleen M Ward, Ayden Scheim, Jonathan Wang, Benjamin Cocchiaro, Katie Singley, Alexis M Roth

Open access · goldAbstract read
In one paragraph

Article in Drug and alcohol dependence reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  3. Induction of Medication for Opioid Use Disorder in Primary Care.Journal of the American Board of Family Medicine : JABFM · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kathleen M WardDepartment of Community Health and Prevention, Dornsife School of Public Health, Drexel University, Philadelphia, PA, United States.
Ayden ScheimDepartment of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA, United States.
Jonathan WangDepartment of Molecular Biology, Princeton University, Princeton, NJ, United States.
Benjamin CocchiaroPrevention Point Philadelphia, Philadelphia, PA, United States.
Katie SingleyDepartment of Community Health and Prevention, Dornsife School of Public Health, Drexel University, Philadelphia, PA, United States.
Alexis M RothDepartment of Community Health and Prevention, Dornsife School of Public Health, Drexel University, Philadelphia, PA, United States.
Drexel University · USCenter Point · USPrinceton University · US

Funding

Training Program in HIV Prevention Research EthicsR25DA031608 · NIDA · FORDHAM UNIVERSITY · PI FISHER, CELIA B · 2011 to 2025
$4.9M
NIDA NIH HHS R25 DA031608
6 · The paper itself

Abstract

Background: Medications such as buprenorphine are considered the gold standard for the treatment of opioid use disorders. This study aimed to determine whether less restrictive buprenorphine prescribing practices during the COVID-19 pandemic impacted retention in and adherence to buprenorphine among patients accessing treatment from 2018-2020 at a community-based syringe services program. Methods: In this retrospective cohort study, we compared retention in treatment before and during the COVID-19 pandemic. Then, with relaxed restrictions acting as the intervention in a natural experiment, we conducted a sub-analysis of "continuity participants" who accessed treatment services both before and during the COVID-19 period. Records of 418 historical control patients treated with buprenorphine before COVID-19 were compared to 88 patients enrolled during COVID-19 (n=43 remote telemedicine and n=45 remote provider with patient on-site). Cox proportional hazards regressions were used to assess risk factors for treatment discontinuation. The sub-analysis used proportion of days covered (PDC) differences before and during COVID-19 (n=164) for a paired analysis in a nonparametric bootstrap test. Results: The risk of discontinuation was 71% lower in those accessing remote telemedicine during COVID-19 (HR=0.29; CI: 0.18, 0.47) and 51% lower in those accessing their remote provider onsite during COVID-19 (HR=0.49; CI:0.31, 0.77), compared to the historical control group. The average PDC did not significantly differ before and during COVID-19 (difference=2.4%; CI:-0.6%, 5.3%). Conclusions: The risk of discontinuing treatment was lower in both COVID-19 treatment groups compared to historical controls. Less restrictive buprenorphine prescribing guidelines during COVID-19 led to improved retention in care over 6-months.

Indexed as

AdherenceBuprenorphineCOVID-19Opioid use disorderPeople who use drugsRetentionTelemedicine

Identifiers

PMID35497489
PMCPMC9040407
OpenAlexW4224443978

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.