ArticleRSC advances2020
Double-edged effects and mechanisms of Zn
Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 80 citations in OpenAlex.
- Oxygen-vacancy-engineered t-ZnO-CeOBioactive materials · 2026Article
- Three-dimensional niche-like porous structure locoregionally regulating macrophage immunosenescence rejuvenates aged bone repair.Bioactive materials · 2026Article
- Dose-dependent effects of zinc oxide nanoparticles on pre-osteoblast cellular response.Scientific reports · 2026Article
- Cytocompatibility Assessment of L-PBF-Manufactured Zinc-Silver-Copper Alloys for Customized Biodegradable Medical Implants.Journal of functional biomaterials · 2026Article
- Multifunctional FePharmaceutics · 2026Article
- (Ca/Zn)COACS omega · 2026Article
- ZIF-8-Based Nanomedicine for Bone Regeneration: A Critical Appraisal of Preclinical Osteoimmunomodulatory Evidence and Translational Readiness.International journal of nanomedicine · 2026Review
- Biodegradable Zinc-Based Alloys for Guided Bone Regeneration Membranes: Feasibility, Current Status, and Future Prospects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Biomedical Applications of Functionalized Composites Based on Metal-Organic Frameworks in Bone Diseases.Pharmaceutics · 2025Review
- Degradable calcium phosphate-coated porous zinc scaffold combined with platelet-rich plasma implantation for rabbit radius defect.European journal of medical research · 2025Article
- Thermoplastic Zinc-Infused Polymer for Chairside Socket Seal Abutments Enhances Antimicrobial and Tissue-Integrative Properties.Antibiotics (Basel, Switzerland) · 2025Article
- The Role of Magnesium, Zinc, and Strontium in Osteoporotic Fracture Repair.Bioengineering (Basel, Switzerland) · 2025Review
- The Combined Effects of Urine Zinc, Cadmium, Mercury, Lead, and Copper on Endometrial Cancer Staging.International journal of environmental research and public health · 2025Article
- Natural potential difference induced functional optimization mechanism for Zn-based multimetal bone implants.Bioactive materials · 2025Article
- Advances in the application and research of biomaterials in promoting bone repair and regeneration through immune modulation.Materials today. Bio · 2025Review
- Enhanced functionalities of biomaterials through metal ion surface modification.Frontiers in bioengineering and biotechnology · 2025Review
- Efficacy of sintered Zinc-doped fluorapatite scaffold as an antimicrobial regenerative bone filler for dental applications.Journal of dentistry · 2024Article
- Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms.Materials today. Bio · 2024Review
- Osteogenesis or Apoptosis-Twofold Effects of ZnACS omega · 2024Article
- Osteoblast Attachment on Bioactive Glass Air Particle Abrasion-Induced Calcium Phosphate Coating.Bioengineering (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc-incorporated biomaterials show promoting effects on osteogenesis; however, excessive zinc ions lead to cytotoxic reactions and also have other adverse effects. Therefore, the double-edged effects of Zn
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.