Evidence map›Paper›PMID 35497071›Full record

ArticleMelanoma management2022

Improved overall survival in dual compared to single immune checkpoint inhibitors in

Adi Kartolo, Cynthia Yeung, Markus Kuksis, Wilma Hopman, Tara Baetz

Abstract read
In one paragraph

Article in Melanoma management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adi KartoloCancer Centre of SouthEastern Ontario, Kingston Health Sciences Centre, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Cynthia YeungCancer Centre of SouthEastern Ontario, Kingston Health Sciences Centre, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.ORCID https://orcid.org/0000-0001-8263-4290
Markus KuksisCancer Centre of SouthEastern Ontario, Kingston Health Sciences Centre, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Wilma HopmanCancer Centre of SouthEastern Ontario, Kingston Health Sciences Centre, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.
Tara BaetzCancer Centre of SouthEastern Ontario, Kingston Health Sciences Centre, Queen's University, 76 Stuart Street, Kingston, ON, K7L 2V7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To evaluate the efficacy of dual versus single immune checkpoint inhibitors (ICI) in Materials & methods: A retrospective study of all advanced Results: Dual ICI had better overall survival (OS) when compared with single ICI in Conclusion: While limited by small sample size and retrospective nature, dual ICI may have non statistically significant trend toward better OS efficacy when compared with single ICI in

Indexed as

BRAF V600 negativeimmune checkpoint inhibitorimmunotherapymelanomametastatic

Identifiers

PMID35497071
PMCPMC9043874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.