Evidence map›Paper›PMID 35497010›Full record

ArticleRSC advances2022

A mild and concise synthesis of aryloxy phosphoramidate prodrug of alcohols

Hanglu Ying, Jie Yao, Fan Wu, Yufen Zhao, Feng Ni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Progress in phosphorylation of natural products.Molecular biology reports · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hanglu YingInstitute of Drug Discovery Technology, Ningbo University Ningbo Zhejiang 315211 P. R. China wufan@nbu.edu.cn nifeng@nbu.edu.cn.
Jie YaoInstitute of Drug Discovery Technology, Ningbo University Ningbo Zhejiang 315211 P. R. China wufan@nbu.edu.cn nifeng@nbu.edu.cn.
Fan WuInstitute of Drug Discovery Technology, Ningbo University Ningbo Zhejiang 315211 P. R. China wufan@nbu.edu.cn nifeng@nbu.edu.cn.ORCID https://orcid.org/0000-0002-0495-6814
Yufen ZhaoInstitute of Drug Discovery Technology, Ningbo University Ningbo Zhejiang 315211 P. R. China wufan@nbu.edu.cn nifeng@nbu.edu.cn.ORCID https://orcid.org/0000-0003-3560-435X
Feng NiInstitute of Drug Discovery Technology, Ningbo University Ningbo Zhejiang 315211 P. R. China wufan@nbu.edu.cn nifeng@nbu.edu.cn.ORCID https://orcid.org/0000-0001-8482-6755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A synthesis of aryloxy phosphoramidate prodrug of alcohols enabled by a transesterification strategy is described here. This reaction operates under mild conditions and thus has excellent functional group tolerance. This method provides an efficient and practical solution to the rapid construction of the aryloxy phosphoramidate prodrugs library for potential SAR studies.

Identifiers

PMID35497010
PMCPMC9052952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.