Evidence map›Paper›PMID 35496898›Full record

ArticleJournal of analytical methods in chemistry2022

Development and Validation of a Liquid Chromatography-Mass Spectrometry Assay for Determination of Cromolyn Sodium in Skin Permeation Studies.

Miranda Kay Holman, Stacy D Brown, Dorcas Frempong, Ashana Puri, Steven Dinh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of analytical methods in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Miranda Kay HolmanDepartment of Biological Sciences, College of Arts and Sciences, East Tennessee State University, TN 37604, Johnson, USA.ORCID https://orcid.org/0000-0001-8175-5453
Stacy D BrownDepartment of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, TN 37604, Johnson, USA.ORCID https://orcid.org/0000-0001-5566-1728
Dorcas FrempongDepartment of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, TN 37604, Johnson, USA.ORCID https://orcid.org/0000-0003-3800-0922
Ashana PuriDepartment of Pharmaceutical Sciences, Bill Gatton College of Pharmacy, East Tennessee State University, TN 37604, Johnson, USA.ORCID https://orcid.org/0000-0002-6685-5808
Steven DinhCollege of Engineering and Computing, Florida International University, FL 33174, Miami, USA.ORCID https://orcid.org/0000-0001-5875-0574
East Tennessee State University · USFlorida International University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cromolyn sodium (CS) is a mast cell stabilizer administered to treat allergic diseases. A topical system would sustain its delivery and may be designed for treatment of atopic dermatitis. Established HPLC protocols for detection of CS are time consuming and intensive, indicating the need for a more streamlined method. This study aimed at developing and validating a sensitive and selective LC-MS method for quantifying CS in skin permeation studies that was less time and resource demanding. The optimized method involved an isocratic mobile phase (10 mM NH

Identifiers

PMID35496898
PMCPMC9050334
OpenAlexW4224295487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.