Evidence map›Paper›PMID 35496512›Full record

ArticleRSC advances2020

Rhenium(i) complexation-dissociation strategy for synthesising fluorine-18 labelled pyridine bidentate radiotracers.

Mitchell A Klenner, Bo Zhang, Gianluca Ciancaleoni, James K Howard, Helen E Maynard-Casely, Jack K Clegg, Massimiliano Massi, Benjamin H Fraser, Giancarlo Pascali

Abstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mitchell A KlennerHuman Health & National Deuteration Facility, Australian Nuclear Science and Technology Organisation (ANSTO) Lucas Heights NSW 2234 Australia gianp@ansto.gov.au bfr@ansto.gov.au.ORCID https://orcid.org/0000-0003-0099-4984
Bo ZhangSchool of Chemistry, Monash University Melbourne VIC 3800 Australia.ORCID https://orcid.org/0000-0002-9199-1115
Gianluca CiancaleoniDipartmento di Chimica e Chimica Industriale, Universit à di Pisa Pisa 56127 Italy.ORCID https://orcid.org/0000-0001-5113-2351
James K HowardHuman Health & National Deuteration Facility, Australian Nuclear Science and Technology Organisation (ANSTO) Lucas Heights NSW 2234 Australia gianp@ansto.gov.au bfr@ansto.gov.au.ORCID https://orcid.org/0000-0002-1764-5919
Helen E Maynard-CaselyHuman Health & National Deuteration Facility, Australian Nuclear Science and Technology Organisation (ANSTO) Lucas Heights NSW 2234 Australia gianp@ansto.gov.au bfr@ansto.gov.au.ORCID https://orcid.org/0000-0001-6364-9665
Jack K CleggSchool of Chemistry and Molecular Biosciences, The University of Queensland St. Lucia QLD 4072 Australia.ORCID https://orcid.org/0000-0002-7140-5596
Massimiliano MassiSchool of Molecular and Life Sciences, Curtin University Bentley WA 6102 Australia.ORCID https://orcid.org/0000-0001-6949-4019
Benjamin H FraserHuman Health & National Deuteration Facility, Australian Nuclear Science and Technology Organisation (ANSTO) Lucas Heights NSW 2234 Australia gianp@ansto.gov.au bfr@ansto.gov.au.ORCID https://orcid.org/0000-0003-3486-5507
Giancarlo PascaliHuman Health & National Deuteration Facility, Australian Nuclear Science and Technology Organisation (ANSTO) Lucas Heights NSW 2234 Australia gianp@ansto.gov.au bfr@ansto.gov.au.ORCID https://orcid.org/0000-0001-7919-8416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel fluorine-18 method employing rhenium(i) mediation is described herein. The method was found to afford moderate to high radiochemical yields of labelled rhenium(i) complexes. Subsequent thermal dissociation of the complexes enabled the radiosynthesis of fluorine-18 labelled pyridine bidentate structures which could not be radiofluorinated hitherto. This rhenium(i) complexation-dissociation strategy was further applied to the radiosynthesis of [

Identifiers

PMID35496512
PMCPMC9049978

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.