ArticleRSC advances2021
Natural deep eutectic solvents as tailored and sustainable media for the extraction of five compounds from compound liquorice tablets and their comparison with conventional organic solvents.
Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Ultrasound-Assisted Deep Eutectic Solvent Extraction of Total Alkaloids fromMolecules (Basel, Switzerland) · 2026Article
- Aqueous bio-based hydrotropic solutions for green extraction of glycyrrhizic acid from licorice: experimental investigation and mechanistic insights.RSC advances · 2026Article
- Safety of NADES Extract ofMolecules (Basel, Switzerland) · 2025Article
- Green Extraction of Polyphenols fromMolecules (Basel, Switzerland) · 2024Article
- Enrichment of Total Flavonoids and Licochalcone A fromMolecules (Basel, Switzerland) · 2024Article
- Optimization of green deep eutectic solvent (DES) extraction ofRSC advances · 2023Article
- The Most Potent Natural Pharmaceuticals, Cosmetics, and Food Ingredients Isolated from Plants with Deep Eutectic Solvents.Journal of agricultural and food chemistry · 2023Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
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Abstract
An efficient and environmentally friendly ultrasound-assisted (UAE) natural deep eutectic solvent (NADES) extraction method was applied for the extraction of five bioactive compounds (liquiritin, isoliquiritin, liquiritigenin, glycyrrhizic acid and isoliquiritigenin) from compound liquorice tablets (CPLTs), and the antioxidant activities of these compounds were evaluated. In this study, eighteen different NADES systems based on either two or three components were tested and a 1,4-butanediol-levulinic acid system (1 : 3 molar ratio) was selected as a topgallant solvent for maximizing analyte extraction yields. Various extraction parameters, such as water content, liquid/solid ratio, extraction time and temperature, were systematically optimized by single-factor and response surface methodology (RSM) experiments. The results indicated that the optimum extraction conditions for the analytes featured a water content of 17%, a liquid/solid ratio of 42 mL g
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