Evidence map›Paper›PMID 35496404›Full record

ArticleRSC advances2021

Novel alkylaminoethyl derivatives of androstane 3-oximes as anticancer candidates: synthesis and evaluation of cytotoxic effects.

Jovana J Ajduković, Dimitar S Jakimov, Lucie Rárová, Miroslav Strnad, Yaraslau U Dzichenka, Sergey Usanov, Dušan Đ Škorić, Suzana S Jovanović-Šanta, Marija N Sakač

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. The structural basis of aldo-keto reductase 1C3 inhibition by 17α-picolyl and 17(Journal of enzyme inhibition and medicinal chemistry · 2025
    Article
  2. Article
  3. Review
  4. A Review of Biologically Active Oxime Ethers.Molecules (Basel, Switzerland) · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Jovana J AjdukovićDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad Serbia jovana.ajdukovic@dh.uns.ac.rs.ORCID https://orcid.org/0000-0003-0218-3640
Dimitar S JakimovOncology Institute of Vojvodina, Faculty of Medicine, University of Novi Sad Put Dr Goldmana 4 21204 Sremska Kamenica Serbia.
Lucie RárováDepartment of Experimental Biology, Faculty of Science, Palacký University Šlechtitelů 27 CZ-78371 Olomouc Czech Republic.
Miroslav StrnadLaboratory of Growth Regulators, Institute of Experimental Botany of the Czech Academy of Sciences, Faculty of Science, Palacký University Šlechtitelů 27 CZ-78371 Olomouc Czech Republic.
Yaraslau U DzichenkaInstitute of Bioorganic Chemistry NAS of Belarus Kuprevicha Street, 5/2 Minsk 220141 Belarus.ORCID https://orcid.org/0000-0002-8655-8704
Sergey UsanovInstitute of Bioorganic Chemistry NAS of Belarus Kuprevicha Street, 5/2 Minsk 220141 Belarus.
Dušan Đ ŠkorićDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad Serbia jovana.ajdukovic@dh.uns.ac.rs.ORCID https://orcid.org/0000-0002-3683-0255
Suzana S Jovanović-ŠantaDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad Serbia jovana.ajdukovic@dh.uns.ac.rs.ORCID https://orcid.org/0000-0002-4579-5762
Marija N SakačDepartment of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad Trg Dositeja Obradovića 3 21000 Novi Sad Serbia jovana.ajdukovic@dh.uns.ac.rs.
University of Novi Sad · RSInstitute of Bioorganic Chemistry · BYCzech Academy of Sciences, Institute of Experimental Botany · CZPalacký University Olomouc · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid anticancer drugs are the focus of numerous scientific research efforts. Due to their high cytotoxic effects against tumor cells, some natural or synthetic steroid compounds seem to be promising for the treatment of different classes of cancer. In the present study, fourteen novel

Identifiers

PMID35496404
PMCPMC9043769
OpenAlexW3217510500

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.