ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2022
Vascular cognitive impairment and dementia: An early career researcher perspective.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- A peripheral perspective on brain health: vascular and skeletal muscle contributions.American journal of physiology. Heart and circulatory physiology · 2026Review
- The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Systemic Piezo1 activation improves cerebrovascular function in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Evaluation of vascular cognitive impairment and identification of imaging markers using machine learning: a multimodal MRI study.Frontiers in neurology · 2025Article
- Associations between selected genetic variants and lipid profile variability in response to statins in Alzheimer's disease: a prospective observational study.Sao Paulo medical journal = Revista paulista de medicina · 2025Observational
- Imaging, biomarkers, and vascular cognitive impairment in China: Rationale and design for the VICA study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Resveratrol Mitigates Cognitive Impairments and Cholinergic Cell Loss in the Medial Septum in a Mouse Model of Gradual Cerebral Hypoperfusion.Antioxidants (Basel, Switzerland) · 2024Article
- Vascular risk, gait, behavioral, and plasma indicators of VCID.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Association of Glycemic Variability With Imaging Markers of Vascular Burden, β-Amyloid, Brain Atrophy, and Cognitive Impairment.Neurology · 2024Article
- Association of white matter hyperintensities with cognitive decline and neurodegeneration.Frontiers in aging neuroscience · 2024Article
- Blood Pressure Variability and Plasma Alzheimer's Disease Biomarkers in the SPRINT Trial.Journal of Alzheimer's disease : JAD · 2024Article
- Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia.International journal of molecular sciences · 2022Review
- Vascular cognitive impairment and dementia: An early career researcher perspective.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- A training program for researchers in population neuroimaging: Early experiences.Frontiers in neuroimaging · 2022Review
- The problem of multiple adjustments in the assessment of minimal clinically important differences.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The field of vascular contributions to cognitive impairment and dementia (VCID) is evolving rapidly. Research in VCID encompasses topics aiming to understand, prevent, and treat the detrimental effects of vascular disease burden in the human brain. In this perspective piece, early career researchers (ECRs) in the field provide an overview of VCID, discuss past and present efforts, and highlight priorities for future research. We emphasize the following critical points as the field progresses: (a) consolidate existing neuroimaging and fluid biomarkers, and establish their utility for pharmacological and non-pharmacological interventions; (b) develop new biomarkers, and new non-clinical models that better recapitulate vascular pathologies; (c) amplify access to emerging biomarker and imaging techniques; (d) validate findings from previous investigations in diverse populations, including those at higher risk of cognitive impairment (e.g., Black, Hispanic, and Indigenous populations); and (e) conduct randomized controlled trials within diverse populations with well-characterized vascular pathologies emphasizing clinically meaningful outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.