Evidence map›Paper›PMID 35496331›Full record

ReviewRSC advances2022

17α-Ethinylestradiol (EE2): concentrations in the environment and methods for wastewater treatment - an update.

Marko Klaic, Franz Jirsa

Abstract readReview
In one paragraph

Review in RSC advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Effects of 17α-Ethinylestradiol on Development and Gonadal Differentiation in the Estuarine Mummichog, Fundulus heteroclitus.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
  2. Production ofMolecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Ecotoxicological evaluation of surface waters in Northern Namibia.Environmental monitoring and assessment · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marko KlaicDepartment of Inorganic Chemistry, University of Vienna Waehringer Str. 42 1090 Vienna Austria franz.jirsa@univie.ac.at.
Franz JirsaDepartment of Inorganic Chemistry, University of Vienna Waehringer Str. 42 1090 Vienna Austria franz.jirsa@univie.ac.at.ORCID https://orcid.org/0000-0002-4926-3261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

17α-Ethinylestradiol (EE2) is a frequently used drug and an endocrine disruptive substance. Adverse effects on biota have been reported when they are exposed to this substance in the environment. The last review on EE2 in the environment was published in 2014. Since then, well above 70 studies on EE2 and related substances have been published. The aim of this review was therefore to bring together recent data with earlier ones. The topics emphasized were observable trends of environmental levels of EE2 and methods to reduce EE2 levels in wastewater, before it can enter the environment. This should give an overview of the recent knowledge and developments regarding these environmental aspects of EE2. In the studies discussed, EE2 levels in surface waters were well detectable in many countries, both above and below the predicted no effect concentration (PNEC) of 0.035 ng L

Identifiers

PMID35496331
PMCPMC9044539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.