Evidence map›Paper›PMID 35495838›Full record

ArticleJournal of family medicine and primary care2022

Syphilis D' Emblée: A case series of the great masquerader.

Murali Narasimhan, Mayank Lagoo, Ramakrishnan Ramachandran, Soosai Donald Fernandes

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of family medicine and primary care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Murali NarasimhanDepartment of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Potheri, Chennai, Tamil Nadu, India.
Mayank LagooDepartment of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Potheri, Chennai, Tamil Nadu, India.
Ramakrishnan RamachandranDepartment of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Potheri, Chennai, Tamil Nadu, India.
Soosai Donald FernandesDepartment of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Potheri, Chennai, Tamil Nadu, India.
ACS Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Syphilis, a chronic infectious disease caused by Treponema pallidum subspecies pallidum, progresses through three arbitrary stages resulting in varied clinical manifestations. The aberrant presentation of syphilis in the secondary stage without any clinical evidence of the primary stage is referred to as syphilis d' emblée. Here we report a series of six cases in male patients. Five out of six patients presented with multiple, non-pruritic, macular palmar, and/or plantar lesions. One patient had typical facial and perianal lesions of condyloma lata. The diagnosis was confirmed by a reactive VDRL with titers ranging from 1:16 to 1:64 and a positive Treponema pallidum hemagglutination assay (TPHA). Syphilis being a great imitator can present in different ways without a typical history of primary chancre following sexual exposure, and can mimic many dermatological disorders in its secondary stage. Unless physicians have a high index of suspicion, the diagnosis may be missed. Early identification aids in prompt initiation of therapy and prevention of disease progression to chronic stages and systemic manifestations.

Indexed as

Syphilissyphilis d’embléeVDRL

Identifiers

PMID35495838
PMCPMC9051677
OpenAlexW4225327444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.