ArticleOrganic chemistry frontiers : an international journal of organic chemistry2022
Decarbonylative Sonogashira Cross-Coupling: Fruitful Marriage of Alkynes with Carboxylic Acid Electrophiles.
Article in Organic chemistry frontiers : an international journal of organic chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 20 citations in OpenAlex.
- Direct Deaminative Alkynylation of Aliphatic Primary Amines.Angewandte Chemie (International ed. in English) · 2026Article
- Ligand Relay for Nickel-Catalyzed Decarbonylative Alkylation of Aroyl Chlorides.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Metal-free highly chemo-selective bisphosphorylation and deoxyphosphorylation of carboxylic acids.Chemical science · 2023Article
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The Sonogashira cross-coupling is one of the most fundamental C-C bond forming reactions, wherein the strategic value of the alkyne moiety has found widespread application at the frontiers of organic chemistry, materials science and drug discovery as the cornerstone building block of chemical synthesis. Although traditional variants of Sonogashira cross-coupling involve aryl halides and pseudohalides as electrophiles, recently, tremendous advances have been made in the unconventional disconnection exploiting common carboxylic acids by decarbonylation/transmetalation pathway. This manifold (1) permits to take advantage of carboxylic acids as a ubiquitous class of substrates in organic synthesis that are derived from an orthogonal pool of precursors to aryl halides and pseudohalides, (2) combines the benefits of the palladium catalyzed C(sp
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Registered trials
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