Evidence map›Paper›PMID 35495558›Full record

ArticleJACC. Case reports2022

First-in-Human Computational Preprocedural Planning of Left Main Interventions Using a New Everolimus-Eluting Stent.

Yiannis S Chatzizisis, Janaki Makadia, Shijia Zhao, Anastasios Panagopoulos, Mohammadali Sharzehee, Behram Khan, Saurabhi Samant, Muhammad Fayaz, Jitendra Pandya, Haysam Akkad and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Revolutionizing Cardiovascular Interventions With Artificial Intelligence.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  3. Artificial Intelligence in Coronary Artery Interventions: Preprocedural Planning and Procedural Assistance.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  4. The everolimus eluting Synergy MegatronCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Yiannis S ChatzizisisCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Janaki MakadiaCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Shijia ZhaoCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Anastasios PanagopoulosCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Mohammadali SharzeheeCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Behram KhanCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Saurabhi SamantCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Muhammad FayazCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Jitendra PandyaCardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Haysam AkkadCardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Gregory PavlidesCardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Edward O'LearyCardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Wei WuCardiovascular Biology and Biomechanics Laboratory, Cardiovascular Division, University of Nebraska Medical Center, Omaha, Nebraska, USA.
University of Nebraska Medical Center · US

Funding

Patient-Specific Simulations to Guide Coronary Bifurcation StentingR01HL144690 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHATZIZISIS, IOANNIS S · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144690
6 · The paper itself

Abstract

Left main coronary artery stenting requires rigorous planning and optimal execution. This case series presents a new approach to left main stenting guided by preprocedural patient-specific computational simulations. Three patients with significant left main artery disease underwent simulation-guided intervention using a novel stent scaffold purpose-built for large coronary arteries. (

Indexed as

3D, 3-dimensionalCAD, coronary artery diseaseCFD, computational fluid dynamicscomputational simulationscoronary artery diseaseHD IVUS, high-definition intravascular ultrasoundimagingLAD, left anterior descendingLCx, left circumflexleft mainLM, left mainPCI, percutaneous coronary interventionpercutaneous coronary interventionsstents

Identifiers

PMID35495558
PMCPMC9040115
OpenAlexW4220931421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.