Evidence map›Paper›PMID 35495469›Full record

ArticleRSC advances2020

Phosphate-sensing with (di-(2-picolyl)amino)quinazolines based on a fluorescence on-off system.

Kazusa Aoki, Ryuji Osako, Jiahui Deng, Takashi Hayashita, Takeshi Hashimoto, Yumiko Suzuki

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. 7-Amino-2-(RSC advances · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Crystal structure of (7-{[bis-(pyridin-2-ylmeth-yl)amino-κActa crystallographica. Section E, Crystallographic communications · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kazusa AokiDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.
Ryuji OsakoDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.
Jiahui DengDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.
Takashi HayashitaDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.ORCID https://orcid.org/0000-0003-1264-9694
Takeshi HashimotoDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.ORCID https://orcid.org/0000-0002-7601-5511
Yumiko SuzukiDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University Kioi-cho 7-1, Chiyoda-ku Tokyo 102-8554 Japan yumiko_suzuki@sophia.ac.jp.ORCID https://orcid.org/0000-0002-8226-5867
Sophia University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detection and visualization of phosphates such as ATP in living organisms can facilitate the elucidation of various biological events. Although substantial efforts had been made in this area, present methods have disadvantages such as the need for specialized equipment and poor sensitivities. To address these limitations, novel fluorescent probes, (di-(2-picolyl)amino)quinazolines, were developed for application in ATP detection. They selectively recognized copper ions by fluorescence quenching, and their copper complexes displayed fluorescence enhancement in the presence of phosphoric acid derivatives. This fluorescence on-off system enabled highly sensitive fluorescence detection of ATP when combined with a phenyl boronic acid-modified γ-cyclodextrin through a plausible multipoint recognition system.

Identifiers

PMID35495469
PMCPMC9052313
OpenAlexW3016813135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.