Evidence map›Paper›PMID 35495466›Full record

ArticleRSC advances2020

Strategic design to create HER2-targeting proteins with target-binding peptides immobilized on a fibronectin type III domain scaffold.

Wanaporn Yimchuen, Tetsuya Kadonosono, Yumi Ota, Shinichi Sato, Maika Kitazawa, Tadashi Shiozawa, Takahiro Kuchimaru, Masumi Taki, Yuji Ito, Hiroyuki Nakamura and 1 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Wanaporn YimchuenSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.
Tetsuya KadonosonoSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.ORCID https://orcid.org/0000-0001-6311-3203
Yumi OtaSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.
Shinichi SatoInstitute of Innovative Research, Tokyo Institute of Technology Yokohama 226-8501 Kanagawa Japan.ORCID https://orcid.org/0000-0002-8563-1658
Maika KitazawaSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.
Tadashi ShiozawaSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.
Takahiro KuchimaruCenter for Molecular Medicine, Jichi Medical University Shimotsuke 329-0498 Japan.ORCID https://orcid.org/0000-0002-5355-3165
Masumi TakiGraduate School of Informatics and Engineering, The University of Electro-Communications Tokyo 182-8585 Japan.ORCID https://orcid.org/0000-0002-1811-8029
Yuji ItoGraduate School of Science and Engineering, Kagoshima University Kagoshima 890-0065 Japan.
Hiroyuki NakamuraInstitute of Innovative Research, Tokyo Institute of Technology Yokohama 226-8501 Kanagawa Japan.ORCID https://orcid.org/0000-0002-4511-2984
Shinae Kizaka-KondohSchool of Life Science and Technology, Tokyo Institute of Technology Yokohama 226-8501 Japan tetsuyak@bio.titech.ac.jp +81-45-924-5848 +81-45-924-5848.ORCID https://orcid.org/0000-0003-3085-5782
Tokyo Institute of Technology · JPJichi Medical University · JPKagoshima University · JPUniversity of Electro-Communications · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-binding peptides such as human epidermal growth factor receptor 2 (HER2)-binding peptides are attractive therapeutic and diagnostic options for cancer. However, the HER2-binding peptides (HBPs) developed thus far are susceptible to proteolysis and lose their affinity to HER2

Identifiers

PMID35495466
PMCPMC9052545
OpenAlexW3016469428

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.