Evidence map›Paper›PMID 35495316›Full record

ArticleRSC advances2020

Synthesis of magnetic nanoparticles with an IDA or TED modified surface for purification and immobilization of poly-histidine tagged proteins.

Kai Zeng, En-Jie Sun, Ze-Wen Liu, Junhui Guo, Chengqing Yuan, Ying Yang, Hao Xie

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Pathogens (Basel, Switzerland) · 2024
    Review
  3. Synthesis of NiAMB Express · 2023
    Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kai ZengSchool of Chemistry, Chemical Engineering, and Life Science, Wuhan University of Technology Wuhan 430070 China sunecho@whut.edu.cn h.xie@whut.edu.cn.
En-Jie SunSchool of Chemistry, Chemical Engineering, and Life Science, Wuhan University of Technology Wuhan 430070 China sunecho@whut.edu.cn h.xie@whut.edu.cn.
Ze-Wen LiuSchool of Chemistry, Chemical Engineering, and Life Science, Wuhan University of Technology Wuhan 430070 China sunecho@whut.edu.cn h.xie@whut.edu.cn.
Junhui GuoSchool of Chemistry, Chemical Engineering, and Life Science, Wuhan University of Technology Wuhan 430070 China sunecho@whut.edu.cn h.xie@whut.edu.cn.
Chengqing YuanSchool of Energy and Power Engineering, Wuhan University of Technology Wuhan 430070 China.
Ying YangInstitute for Science and Technology in Medicine, Keele University Staffordshire ST4 7QB UK.ORCID https://orcid.org/0000-0002-1362-6040
Hao XieSchool of Chemistry, Chemical Engineering, and Life Science, Wuhan University of Technology Wuhan 430070 China sunecho@whut.edu.cn h.xie@whut.edu.cn.ORCID https://orcid.org/0000-0001-5981-1666
Wuhan University of Technology · CNKeele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic nanoparticles (MNPs) chelating with metal ions can specifically interact with poly-histidine peptides and facilitate immobilization and purification of proteins with poly-histidine tags. Fabrication of MNPs is generally complicated and time consuming. In this paper, we report the preparation of Ni(ii) ion chelated MNPs (Ni-MNPs) in two stages for protein immobilization and purification. In the first stage, organic ligands including pentadentate tris (carboxymethyl) ethylenediamine (TED) and tridentate iminodiacetic acid (IDA) and inorganic Fe

Identifiers

PMID35495316
PMCPMC9050487
OpenAlexW3011291335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.