ArticleHardwareX2020
Low-cost, open-source, variable speed and incline treadmill for studying impacts of neonatal locomotion.
Article in HardwareX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Evaluating Gait and Locomotion in Rodents with the CatWalk.Current protocols · 2021Article
- An open-source, lockable mouse wheel for the accessible implementation of time- and distance-limited elective exercise.PloS one · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a need for a small-scale, laboratory treadmill to investigate impacts of neonatal locomotion on neuromuscular and musculoskeletal development in small animal models. Adult mice and rats are routinely assessed using commercially available treadmills, but these treadmills can be relatively expensive and they may lack features needed to evaluate developing animals. Therefore, to overcome these limitations, a new treadmill was designed, built and calibrated. This open-source treadmill was designed specifically for neonatal and postnatal mice and rats, and it fits within a neonatal incubator. By using predominantly off-the-shelf and 3D printed components, and a microcontroller, this treadmill was low cost and easy to reproduce. The design also included variable incline, and a transparent belt and enclosures for video and gait analysis. A touchscreen interface provided user-friendly control over belt speed and run time. Moreover, validation experiments showed high accuracy in belt speed control, allowing for tightly regulated experimental conditions. Overall, this new low-cost, open-source, variable speed and incline treadmill can be used to advance understanding of neonatal locomotion, and neuromuscular and musculoskeletal development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.